STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZP3Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, which mediates species- specific sperm binding. Directly binds to sperm. Important for egg fertilization; Belongs to the ZP domain family. ZPC subfamily. (437 aa)    
Predicted Functional Partners:
UMOD
Zona pellucida protein D.
   
  
 0.955
ZPAX
Zona pellucida protein.
   
  
 0.871
ZP4
Uncharacterized protein.
      
 0.815
ZP2
ZP domain-containing protein.
   
  
 0.772
ADGRL3
Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.
    
   0.613
ADGRL2
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
   0.613
TECTA
Alpha-tectorin; One of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals.
   
  
 0.593
LOC100857892
NIDO domain-containing protein.
      
 0.588
SPRN
Shadow of prion protein; Prion-like protein that has PrP(C)-like neuroprotective activity; Belongs to the SPRN family.
      
 0.586
BTG4
Anti_prolifrtn domain-containing protein.
   
  
 0.554
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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