node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANGPT1 | GRB2 | ENSGALP00000050106 | ENSGALP00000012993 | Fibrinogen C-terminal domain-containing protein. | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | 0.477 |
ANGPT1 | KITLG | ENSGALP00000050106 | ENSGALP00000018246 | Fibrinogen C-terminal domain-containing protein. | Processed kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Acts synergistically with other cytokines, probably interleukins (By similarity). | 0.422 |
ANGPT1 | PDGFB | ENSGALP00000050106 | ENSGALP00000019858 | Fibrinogen C-terminal domain-containing protein. | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. | 0.736 |
ANGPT1 | PGF | ENSGALP00000050106 | ENSGALP00000065908 | Fibrinogen C-terminal domain-containing protein. | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. | 0.692 |
ANGPT1 | TEK | ENSGALP00000050106 | ENSGALP00000072046 | Fibrinogen C-terminal domain-containing protein. | TEK receptor tyrosine kinase. | 0.990 |
ANGPT1 | VEGFC | ENSGALP00000050106 | ENSGALP00000017608 | Fibrinogen C-terminal domain-containing protein. | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. | 0.722 |
ANGPT1 | VEGFD | ENSGALP00000050106 | ENSGALP00000055963 | Fibrinogen C-terminal domain-containing protein. | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. | 0.602 |
ANGPT2 | PDGFB | ENSGALP00000064997 | ENSGALP00000019858 | Angiopoietin-2A. | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. | 0.729 |
ANGPT2 | PGF | ENSGALP00000064997 | ENSGALP00000065908 | Angiopoietin-2A. | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. | 0.702 |
ANGPT2 | TEK | ENSGALP00000064997 | ENSGALP00000072046 | Angiopoietin-2A. | TEK receptor tyrosine kinase. | 0.994 |
ANGPT2 | VEGFC | ENSGALP00000064997 | ENSGALP00000017608 | Angiopoietin-2A. | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. | 0.773 |
ANGPT2 | VEGFD | ENSGALP00000064997 | ENSGALP00000055963 | Angiopoietin-2A. | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. | 0.518 |
ANGPT4 | TEK | ENSGALP00000058314 | ENSGALP00000072046 | Angiopoietin 4. | TEK receptor tyrosine kinase. | 0.989 |
GRB2 | ANGPT1 | ENSGALP00000012993 | ENSGALP00000050106 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | Fibrinogen C-terminal domain-containing protein. | 0.477 |
GRB2 | KITLG | ENSGALP00000012993 | ENSGALP00000018246 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | Processed kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Acts synergistically with other cytokines, probably interleukins (By similarity). | 0.528 |
GRB2 | PDGFB | ENSGALP00000012993 | ENSGALP00000019858 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. | 0.456 |
GRB2 | TEK | ENSGALP00000012993 | ENSGALP00000072046 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | TEK receptor tyrosine kinase. | 0.747 |
KITLG | ANGPT1 | ENSGALP00000018246 | ENSGALP00000050106 | Processed kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Acts synergistically with other cytokines, probably interleukins (By similarity). | Fibrinogen C-terminal domain-containing protein. | 0.422 |
KITLG | GRB2 | ENSGALP00000018246 | ENSGALP00000012993 | Processed kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Acts synergistically with other cytokines, probably interleukins (By similarity). | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | 0.528 |
KITLG | TEK | ENSGALP00000018246 | ENSGALP00000072046 | Processed kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Acts synergistically with other cytokines, probably interleukins (By similarity). | TEK receptor tyrosine kinase. | 0.808 |