STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
R3HDM4R3H domain containing 4. (263 aa)    
Predicted Functional Partners:
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
   
 
 0.938
C5H14orf1
Uncharacterized protein.
   
 
 0.913
FDFT1
Uncharacterized protein.
   
 
 0.752
NDUFAF6
NADH:ubiquinone oxidoreductase complex assembly factor 6.
   
 
 0.752
DHCR7
Uncharacterized protein.
   
 
 0.682
LBR
Delta(14)-sterol reductase LBR; Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis (By similarity). Anchors the lamina and the heterochromatin to the inner nuclear membrane (By similarity). Belongs to the ERG4/ERG24 family.
   
 
 0.682
CH25H
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 0.656
MSMO1
Methylsterol monooxygenase 1; Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol; Belongs to the sterol desaturase family.
   
 0.656
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.656
FAXDC2
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 0.656
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.