node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COP1 | CTTNBP2NL | ENSGALP00000072721 | ENSGALP00000041570 | COP1 E3 ubiquitin ligase. | CTTNBP2 N-terminal like. | 0.499 |
COP1 | GOT1 | ENSGALP00000072721 | ENSGALP00000012086 | COP1 E3 ubiquitin ligase. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.478 |
COP1 | SETD6 | ENSGALP00000072721 | ENSGALP00000003512 | COP1 E3 ubiquitin ligase. | N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. | 0.587 |
CTTNBP2NL | COP1 | ENSGALP00000041570 | ENSGALP00000072721 | CTTNBP2 N-terminal like. | COP1 E3 ubiquitin ligase. | 0.499 |
CTTNBP2NL | GOT1 | ENSGALP00000041570 | ENSGALP00000012086 | CTTNBP2 N-terminal like. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.536 |
CTTNBP2NL | SETD6 | ENSGALP00000041570 | ENSGALP00000003512 | CTTNBP2 N-terminal like. | N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. | 0.702 |
DNAJC8 | RPS27L | ENSGALP00000067055 | ENSGALP00000065928 | DnaJ heat shock protein family (Hsp40) member C8. | 40S ribosomal protein S27. | 0.601 |
DNAJC8 | SETD6 | ENSGALP00000067055 | ENSGALP00000003512 | DnaJ heat shock protein family (Hsp40) member C8. | N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. | 0.709 |
DNAJC8 | TCEA1 | ENSGALP00000067055 | ENSGALP00000044127 | DnaJ heat shock protein family (Hsp40) member C8. | Uncharacterized protein. | 0.717 |
GAMT | NOB1 | ENSGALP00000072854 | ENSGALP00000000975 | RMT2 domain-containing protein. | RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. | 0.405 |
GAMT | SETD4 | ENSGALP00000072854 | ENSGALP00000025766 | RMT2 domain-containing protein. | SET domain-containing protein. | 0.540 |
GAMT | SETD6 | ENSGALP00000072854 | ENSGALP00000003512 | RMT2 domain-containing protein. | N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. | 0.574 |
GOT1 | COP1 | ENSGALP00000012086 | ENSGALP00000072721 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | COP1 E3 ubiquitin ligase. | 0.478 |
GOT1 | CTTNBP2NL | ENSGALP00000012086 | ENSGALP00000041570 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | CTTNBP2 N-terminal like. | 0.536 |
GOT1 | SETD6 | ENSGALP00000012086 | ENSGALP00000003512 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. | 0.625 |
NOB1 | GAMT | ENSGALP00000000975 | ENSGALP00000072854 | RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. | RMT2 domain-containing protein. | 0.405 |
NOB1 | RPS27L | ENSGALP00000000975 | ENSGALP00000065928 | RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. | 40S ribosomal protein S27. | 0.659 |
NOB1 | SETD6 | ENSGALP00000000975 | ENSGALP00000003512 | RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. | N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. | 0.756 |
RELA | SETD6 | ENSGALP00000047666 | ENSGALP00000003512 | Transcription factor p65; NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain- containing proteins. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites tha [...] | N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. | 0.828 |
RPS27L | DNAJC8 | ENSGALP00000065928 | ENSGALP00000067055 | 40S ribosomal protein S27. | DnaJ heat shock protein family (Hsp40) member C8. | 0.601 |