STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB41Zinc finger and BTB domain containing 41. (905 aa)    
Predicted Functional Partners:
BRWD1
Bromodomain and WD repeat domain containing 1.
   
 
 0.821
PCGF5
RING-type domain-containing protein.
   
 
 0.724
YOD1
Ubiquitin thioesterase OTU1; Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains. A [...]
   
  
 0.716
HELZ
Helicase with zinc finger.
      
 0.708
SNX16
PX domain-containing protein.
   
  
 0.706
KCNT2
Potassium sodium-activated channel subfamily T member 2.
      
 0.705
WDR82
WD repeat-containing protein 82; Component of a chromatin regulatory complex involved in regulating chromatin structure in the nucleus; Belongs to the WD repeat SWD2 family.
      
 0.667
CAMSAP2
Calmodulin regulated spectrin associated protein family member 2.
   
  
 0.626
USP44
Ubiquitin carboxyl-terminal hydrolase.
   
 
 0.620
CCNT2
Uncharacterized protein.
   
  
 0.551
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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