STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RFNGBeta-1,3-N-acetylglucosaminyltransferase radical fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (By similarity). Plays an important role in limb outgrowth, it directs the formation and positioning of the apical ectodermal ridge (AER), one of the key organizer centers of vertebrate limb development. (372 aa)    
Predicted Functional Partners:
NOTCH1
Uncharacterized protein.
    
 0.921
NOTCH2
Uncharacterized protein.
    
 0.913
MFNG
Beta-1,3-N-acetylglucosaminyltransferase.
  
  
0.905
LFNG
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Essential mediator of somite segmentation and patterning.
  
  
0.903
B3GALNT1
Hexosyltransferase.
   
 
 0.758
A4GALT
Gb3_synth domain-containing protein.
   
  
 0.743
POFUT1
Uncharacterized protein POFUT1.
   
  
 0.636
CHPF
Hexosyltransferase.
   
  
 0.616
DLL1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 
 0.505
NELFB
Uncharacterized protein.
   
 
 0.483
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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