node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMBRA1 | ATG12 | ENSGALP00000037597 | ENSGALP00000003688 | Autophagy and beclin 1 regulator 1. | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | 0.836 |
AMBRA1 | ATG14 | ENSGALP00000037597 | ENSGALP00000019815 | Autophagy and beclin 1 regulator 1. | Autophagy related 14. | 0.963 |
AMBRA1 | ATG5 | ENSGALP00000037597 | ENSGALP00000050539 | Autophagy and beclin 1 regulator 1. | Autophagy protein 5; Involved in autophagic vesicle formation. | 0.791 |
AMBRA1 | BCL2 | ENSGALP00000037597 | ENSGALP00000020984 | Autophagy and beclin 1 regulator 1. | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). | 0.753 |
AMBRA1 | BECN1 | ENSGALP00000037597 | ENSGALP00000004697 | Autophagy and beclin 1 regulator 1. | Beclin-1; Plays a central role in autophagy (By similarity). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways such as initiation of autophagosomes, maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Belongs to the beclin family. | 0.997 |
AMBRA1 | PIK3C3 | ENSGALP00000037597 | ENSGALP00000072284 | Autophagy and beclin 1 regulator 1. | Phosphatidylinositol 3-kinase catalytic subunit type 3. | 0.829 |
AMBRA1 | PIK3R4 | ENSGALP00000037597 | ENSGALP00000051290 | Autophagy and beclin 1 regulator 1. | Phosphoinositide-3-kinase regulatory subunit 4. | 0.750 |
AMBRA1 | ULK1 | ENSGALP00000037597 | ENSGALP00000052115 | Autophagy and beclin 1 regulator 1. | Unc-51 like autophagy activating kinase 1. | 0.972 |
AMBRA1 | UVRAG | ENSGALP00000037597 | ENSGALP00000051951 | Autophagy and beclin 1 regulator 1. | C2 domain-containing protein. | 0.978 |
ATG12 | AMBRA1 | ENSGALP00000003688 | ENSGALP00000037597 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Autophagy and beclin 1 regulator 1. | 0.836 |
ATG12 | ATG14 | ENSGALP00000003688 | ENSGALP00000019815 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Autophagy related 14. | 0.959 |
ATG12 | ATG5 | ENSGALP00000003688 | ENSGALP00000050539 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Autophagy protein 5; Involved in autophagic vesicle formation. | 0.999 |
ATG12 | BCL2 | ENSGALP00000003688 | ENSGALP00000020984 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). | 0.816 |
ATG12 | BCL2L1 | ENSGALP00000003688 | ENSGALP00000054103 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Bcl-2-like protein 1; Dominant regulator of apoptotic cell death. The long form displays cell death repressor activity, whereas the short isoform promotes apoptosis. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis (By similarity). | 0.444 |
ATG12 | BECN1 | ENSGALP00000003688 | ENSGALP00000004697 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Beclin-1; Plays a central role in autophagy (By similarity). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways such as initiation of autophagosomes, maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Belongs to the beclin family. | 0.990 |
ATG12 | PIK3C3 | ENSGALP00000003688 | ENSGALP00000072284 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Phosphatidylinositol 3-kinase catalytic subunit type 3. | 0.941 |
ATG12 | PIK3R4 | ENSGALP00000003688 | ENSGALP00000051290 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Phosphoinositide-3-kinase regulatory subunit 4. | 0.839 |
ATG12 | ULK1 | ENSGALP00000003688 | ENSGALP00000052115 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | Unc-51 like autophagy activating kinase 1. | 0.962 |
ATG12 | UVRAG | ENSGALP00000003688 | ENSGALP00000051951 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. | C2 domain-containing protein. | 0.910 |
ATG14 | AMBRA1 | ENSGALP00000019815 | ENSGALP00000037597 | Autophagy related 14. | Autophagy and beclin 1 regulator 1. | 0.963 |