node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP6AP1 | ATP6V0A2 | ENSGALP00000014341 | ENSGALP00000005054 | Uncharacterized protein. | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | 0.980 |
ATP6AP1 | ATP6V0B | ENSGALP00000014341 | ENSGALP00000062531 | Uncharacterized protein. | Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. | 0.999 |
ATP6AP1 | ATP6V0C | ENSGALP00000014341 | ENSGALP00000015002 | Uncharacterized protein. | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.998 |
ATP6AP1 | ATP6V0D1 | ENSGALP00000014341 | ENSGALP00000003494 | Uncharacterized protein. | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. | 0.998 |
ATP6AP1 | ATP6V0D2 | ENSGALP00000014341 | ENSGALP00000052021 | Uncharacterized protein. | V-type proton ATPase subunit d 2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity); Belongs to the V-ATPase V0D/AC39 subunit family. | 0.995 |
ATP6AP1 | ATP6V1A | ENSGALP00000014341 | ENSGALP00000070489 | Uncharacterized protein. | V-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. May play a role in neurite development and synaptic connectivity. Belongs to the ATPase alpha/beta chains family. | 0.980 |
ATP6AP1 | ATP6V1B2 | ENSGALP00000014341 | ENSGALP00000054654 | Uncharacterized protein. | V-type proton ATPase subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells; Belongs to the ATPase alpha/beta chains family. | 0.959 |
ATP6AP1 | ATP6V1E1 | ENSGALP00000014341 | ENSGALP00000021250 | Uncharacterized protein. | Uncharacterized protein. | 0.994 |
ATP6AP1 | ATP6V1H | ENSGALP00000014341 | ENSGALP00000022123 | Uncharacterized protein. | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. | 0.997 |
ATP6AP1 | LOC107049680 | ENSGALP00000014341 | ENSGALP00000068721 | Uncharacterized protein. | ATP-synt_ab domain-containing protein. | 0.953 |
ATP6V0A2 | ATP6AP1 | ENSGALP00000005054 | ENSGALP00000014341 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | Uncharacterized protein. | 0.980 |
ATP6V0A2 | ATP6V0B | ENSGALP00000005054 | ENSGALP00000062531 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. | 0.993 |
ATP6V0A2 | ATP6V0C | ENSGALP00000005054 | ENSGALP00000015002 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.993 |
ATP6V0A2 | ATP6V0D1 | ENSGALP00000005054 | ENSGALP00000003494 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. | 0.988 |
ATP6V0A2 | ATP6V0D2 | ENSGALP00000005054 | ENSGALP00000052021 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | V-type proton ATPase subunit d 2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity); Belongs to the V-ATPase V0D/AC39 subunit family. | 0.988 |
ATP6V0A2 | ATP6V1A | ENSGALP00000005054 | ENSGALP00000070489 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | V-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. May play a role in neurite development and synaptic connectivity. Belongs to the ATPase alpha/beta chains family. | 0.970 |
ATP6V0A2 | ATP6V1B2 | ENSGALP00000005054 | ENSGALP00000054654 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | V-type proton ATPase subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells; Belongs to the ATPase alpha/beta chains family. | 0.977 |
ATP6V0A2 | ATP6V1E1 | ENSGALP00000005054 | ENSGALP00000021250 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | Uncharacterized protein. | 0.988 |
ATP6V0A2 | ATP6V1H | ENSGALP00000005054 | ENSGALP00000022123 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. | 0.984 |
ATP6V0A2 | LOC107049680 | ENSGALP00000005054 | ENSGALP00000068721 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | ATP-synt_ab domain-containing protein. | 0.972 |