node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASCL1 | FOXA2 | ENSGALP00000047577 | ENSGALP00000044955 | BHLH domain-containing protein. | Fork-head domain-containing protein. | 0.749 |
ASCL1 | FOXG1 | ENSGALP00000047577 | ENSGALP00000054672 | BHLH domain-containing protein. | Forkhead box protein G1; May determine the nasotemporal axis of the retina, and consequently specify the topographical projection of the retinal ganglion-cell axons to the tectum by controlling expression of their target genes. | 0.650 |
ASCL1 | LMX1A | ENSGALP00000047577 | ENSGALP00000005401 | BHLH domain-containing protein. | Uncharacterized protein. | 0.728 |
ASCL1 | OTX2 | ENSGALP00000047577 | ENSGALP00000045234 | BHLH domain-containing protein. | Homeodomain transcription factor. | 0.712 |
ASCL1 | PAX2 | ENSGALP00000047577 | ENSGALP00000045193 | BHLH domain-containing protein. | Paired-box containing protein Pax-2. | 0.553 |
ASCL1 | SHH | ENSGALP00000047577 | ENSGALP00000010292 | BHLH domain-containing protein. | Sonic hedgehog protein N-product; [Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.716 |
ASCL1 | TH | ENSGALP00000047577 | ENSGALP00000051175 | BHLH domain-containing protein. | Tyrosine hydroxylase. | 0.705 |
FOXA2 | ASCL1 | ENSGALP00000044955 | ENSGALP00000047577 | Fork-head domain-containing protein. | BHLH domain-containing protein. | 0.749 |
FOXA2 | LMX1A | ENSGALP00000044955 | ENSGALP00000005401 | Fork-head domain-containing protein. | Uncharacterized protein. | 0.863 |
FOXA2 | MSX1 | ENSGALP00000044955 | ENSGALP00000024163 | Fork-head domain-containing protein. | Homeobox protein GHOX-7; Probably plays a role in patterning events during embryonic limb development. May also be involved in programmed cell death. | 0.533 |
FOXA2 | OTX2 | ENSGALP00000044955 | ENSGALP00000045234 | Fork-head domain-containing protein. | Homeodomain transcription factor. | 0.846 |
FOXA2 | SHH | ENSGALP00000044955 | ENSGALP00000010292 | Fork-head domain-containing protein. | Sonic hedgehog protein N-product; [Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.858 |
FOXA2 | TH | ENSGALP00000044955 | ENSGALP00000051175 | Fork-head domain-containing protein. | Tyrosine hydroxylase. | 0.655 |
FOXA2 | WNT1 | ENSGALP00000044955 | ENSGALP00000071904 | Fork-head domain-containing protein. | Protein Wnt-1; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. Developmental protein that promotes cell proliferation in the developing spinal cord. Has a role in osteoblast function, bone development and bone homeostasis (By similarity). | 0.459 |
FOXG1 | ASCL1 | ENSGALP00000054672 | ENSGALP00000047577 | Forkhead box protein G1; May determine the nasotemporal axis of the retina, and consequently specify the topographical projection of the retinal ganglion-cell axons to the tectum by controlling expression of their target genes. | BHLH domain-containing protein. | 0.650 |
FOXG1 | LMX1A | ENSGALP00000054672 | ENSGALP00000005401 | Forkhead box protein G1; May determine the nasotemporal axis of the retina, and consequently specify the topographical projection of the retinal ganglion-cell axons to the tectum by controlling expression of their target genes. | Uncharacterized protein. | 0.687 |
FOXG1 | MSX1 | ENSGALP00000054672 | ENSGALP00000024163 | Forkhead box protein G1; May determine the nasotemporal axis of the retina, and consequently specify the topographical projection of the retinal ganglion-cell axons to the tectum by controlling expression of their target genes. | Homeobox protein GHOX-7; Probably plays a role in patterning events during embryonic limb development. May also be involved in programmed cell death. | 0.482 |
FOXG1 | OTX2 | ENSGALP00000054672 | ENSGALP00000045234 | Forkhead box protein G1; May determine the nasotemporal axis of the retina, and consequently specify the topographical projection of the retinal ganglion-cell axons to the tectum by controlling expression of their target genes. | Homeodomain transcription factor. | 0.818 |
FOXG1 | PAX2 | ENSGALP00000054672 | ENSGALP00000045193 | Forkhead box protein G1; May determine the nasotemporal axis of the retina, and consequently specify the topographical projection of the retinal ganglion-cell axons to the tectum by controlling expression of their target genes. | Paired-box containing protein Pax-2. | 0.719 |
FOXG1 | SHH | ENSGALP00000054672 | ENSGALP00000010292 | Forkhead box protein G1; May determine the nasotemporal axis of the retina, and consequently specify the topographical projection of the retinal ganglion-cell axons to the tectum by controlling expression of their target genes. | Sonic hedgehog protein N-product; [Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.727 |