node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHUK | PTEN | ENSGALP00000051589 | ENSGALP00000005747 | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.939 |
INPP4B | PIK3C3 | ENSGALP00000057972 | ENSGALP00000072284 | Inositol polyphosphate-4-phosphatase type II B. | Phosphatidylinositol 3-kinase catalytic subunit type 3. | 0.911 |
INPP4B | PIK3CA | ENSGALP00000057972 | ENSGALP00000014504 | Inositol polyphosphate-4-phosphatase type II B. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.407 |
INPP4B | PIK3R1 | ENSGALP00000057972 | ENSGALP00000067669 | Inositol polyphosphate-4-phosphatase type II B. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.907 |
INPP4B | PIK3R2 | ENSGALP00000057972 | ENSGALP00000005414 | Inositol polyphosphate-4-phosphatase type II B. | Uncharacterized protein. | 0.907 |
INPP4B | PIK3R3 | ENSGALP00000057972 | ENSGALP00000023820 | Inositol polyphosphate-4-phosphatase type II B. | Uncharacterized protein. | 0.907 |
INPP4B | PTEN | ENSGALP00000057972 | ENSGALP00000005747 | Inositol polyphosphate-4-phosphatase type II B. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.957 |
PIK3C3 | INPP4B | ENSGALP00000072284 | ENSGALP00000057972 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Inositol polyphosphate-4-phosphatase type II B. | 0.911 |
PIK3C3 | PIK3CA | ENSGALP00000072284 | ENSGALP00000014504 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.662 |
PIK3C3 | PIK3CB | ENSGALP00000072284 | ENSGALP00000008740 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.652 |
PIK3C3 | PIK3CD | ENSGALP00000072284 | ENSGALP00000004061 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.631 |
PIK3C3 | PIK3R1 | ENSGALP00000072284 | ENSGALP00000067669 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.916 |
PIK3C3 | PIK3R2 | ENSGALP00000072284 | ENSGALP00000005414 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Uncharacterized protein. | 0.919 |
PIK3C3 | PIK3R3 | ENSGALP00000072284 | ENSGALP00000023820 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Uncharacterized protein. | 0.904 |
PIK3C3 | PTEN | ENSGALP00000072284 | ENSGALP00000005747 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.936 |
PIK3CA | INPP4B | ENSGALP00000014504 | ENSGALP00000057972 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | Inositol polyphosphate-4-phosphatase type II B. | 0.407 |
PIK3CA | PIK3C3 | ENSGALP00000014504 | ENSGALP00000072284 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | Phosphatidylinositol 3-kinase catalytic subunit type 3. | 0.662 |
PIK3CA | PIK3CB | ENSGALP00000014504 | ENSGALP00000008740 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.965 |
PIK3CA | PIK3CD | ENSGALP00000014504 | ENSGALP00000004061 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.961 |
PIK3CA | PIK3R1 | ENSGALP00000014504 | ENSGALP00000067669 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.994 |