STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MKRN2Uncharacterized protein. (417 aa)    
Predicted Functional Partners:
TSEN2
tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...]
 
    
 0.767
AGAP1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1.
      
 0.741
HAGH
Hydroxyacylglutathione hydrolase, mitochondrial; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
 
 
  
 0.734
USP42
Uncharacterized protein.
   
  
 0.711
SETD5
SET domain-containing protein.
      
 0.707
HAGHL
Hydroxyacylglutathione hydrolase-like protein; Hydrolase acting on ester bonds; Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
 
 
  
 0.687
DUOXA2
Uncharacterized protein.
      
 0.667
CAMSAP2
Calmodulin regulated spectrin associated protein family member 2.
   
  
 0.623
SRSF7
Uncharacterized protein.
      
 0.541
CEP131
Centrosomal protein 131.
    
 
 0.539
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.