STRINGSTRING
MCM2 protein (Gallus gallus) - STRING interaction network
"MCM2" - DNA helicase in Gallus gallus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCM2DNA helicase; Gallus gallus minichromosome maintenance complex component 2 (MCM2), mRNA; Belongs to the MCM family (888 aa)    
Predicted Functional Partners:
MCM5
DNA helicase; Gallus gallus minichromosome maintenance complex component 5 (MCM5), mRNA; Belongs to the MCM family (734 aa)
     
0.999
MCM6
DNA helicase; Gallus gallus minichromosome maintenance complex component 6 (MCM6), mRNA; Belongs to the MCM family (915 aa)
   
0.999
MCM3
DNA replication licensing factor MCM3; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (869 aa)
     
0.999
MCM4
DNA helicase; Minichromosome maintenance complex component 4; Belongs to the MCM family (859 aa)
   
0.999
CDC45
Cell division cycle 45 (597 aa)
     
  0.999
ORC1
Gallus gallus origin recognition complex, subunit 1 (ORC1), mRNA (858 aa)
   
  0.999
POLA2
Uncharacterized protein; Polymerase (DNA directed), alpha 2, accessory subunit (245 aa)
     
  0.999
ORC2
Gallus gallus origin recognition complex, subunit 2 (ORC2), mRNA (569 aa)
     
  0.998
CDT1
Chromatin licensing and DNA replication factor 1 (587 aa)
     
  0.998
POLA1
Polymerase (DNA directed), alpha 1, catalytic subunit (1491 aa)
     
  0.998
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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