STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB46Zinc finger and BTB domain containing 46. (799 aa)    
Predicted Functional Partners:
BATF3
Basic leucine zipper ATF-like transcription factor 3.
    
 
 0.798
FLT3
Fms related tyrosine kinase 3.
    
 
 0.742
XCR1
CCXC chemokine receptor 1 like.
   
  
 0.715
IRF8
Interferon regulatory factor 8; Plays a role as a transcriptional activator or repressor. Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune system (By similarity); Belongs to the IRF family.
   
 
 0.706
C22H2ORF42
Zf-tcix domain-containing protein.
   
  
 0.681
GLP1R
Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.
      
 0.668
LY75
Uncharacterized protein.
   
 
 0.661
GMEB2
Glucocorticoid modulatory element binding protein 2.
   
 
 0.610
ZGPAT
Uncharacterized protein.
   
  
 0.605
CALCR
Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.
   
  
 0.589
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.