node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMBRA1 | BECN1 | ENSGALP00000037597 | ENSGALP00000004697 | Autophagy and beclin 1 regulator 1. | Beclin-1; Plays a central role in autophagy (By similarity). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways such as initiation of autophagosomes, maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Belongs to the beclin family. | 0.997 |
AMBRA1 | PIK3C3 | ENSGALP00000037597 | ENSGALP00000072284 | Autophagy and beclin 1 regulator 1. | Phosphatidylinositol 3-kinase catalytic subunit type 3. | 0.829 |
AMBRA1 | SH3GLB1 | ENSGALP00000037597 | ENSGALP00000047220 | Autophagy and beclin 1 regulator 1. | Endophilin-B1; May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion (By similarity). Belongs to the endophilin family. | 0.627 |
AMBRA1 | UVRAG | ENSGALP00000037597 | ENSGALP00000051951 | Autophagy and beclin 1 regulator 1. | C2 domain-containing protein. | 0.978 |
BCAP29 | SH3GLB1 | ENSGALP00000012985 | ENSGALP00000047220 | Uncharacterized protein. | Endophilin-B1; May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion (By similarity). Belongs to the endophilin family. | 0.606 |
BECN1 | AMBRA1 | ENSGALP00000004697 | ENSGALP00000037597 | Beclin-1; Plays a central role in autophagy (By similarity). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways such as initiation of autophagosomes, maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Belongs to the beclin family. | Autophagy and beclin 1 regulator 1. | 0.997 |
BECN1 | PIK3C3 | ENSGALP00000004697 | ENSGALP00000072284 | Beclin-1; Plays a central role in autophagy (By similarity). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways such as initiation of autophagosomes, maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Belongs to the beclin family. | Phosphatidylinositol 3-kinase catalytic subunit type 3. | 0.999 |
BECN1 | SH3GLB1 | ENSGALP00000004697 | ENSGALP00000047220 | Beclin-1; Plays a central role in autophagy (By similarity). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways such as initiation of autophagosomes, maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Belongs to the beclin family. | Endophilin-B1; May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion (By similarity). Belongs to the endophilin family. | 0.596 |
BECN1 | UVRAG | ENSGALP00000004697 | ENSGALP00000051951 | Beclin-1; Plays a central role in autophagy (By similarity). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways such as initiation of autophagosomes, maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Belongs to the beclin family. | C2 domain-containing protein. | 0.999 |
CLCA1 | ODF2L | ENSGALP00000010208 | ENSGALP00000055453 | Chloride channel accessory 1. | Outer dense fiber of sperm tails 2 like. | 0.733 |
CLCA1 | SH3GLB1 | ENSGALP00000010208 | ENSGALP00000047220 | Chloride channel accessory 1. | Endophilin-B1; May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion (By similarity). Belongs to the endophilin family. | 0.542 |
FARSB | SH3GLB1 | ENSGALP00000008398 | ENSGALP00000047220 | B5 domain-containing protein. | Endophilin-B1; May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion (By similarity). Belongs to the endophilin family. | 0.633 |
ODF2L | CLCA1 | ENSGALP00000055453 | ENSGALP00000010208 | Outer dense fiber of sperm tails 2 like. | Chloride channel accessory 1. | 0.733 |
ODF2L | SH3GLB1 | ENSGALP00000055453 | ENSGALP00000047220 | Outer dense fiber of sperm tails 2 like. | Endophilin-B1; May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion (By similarity). Belongs to the endophilin family. | 0.908 |
PIK3C3 | AMBRA1 | ENSGALP00000072284 | ENSGALP00000037597 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Autophagy and beclin 1 regulator 1. | 0.829 |
PIK3C3 | BECN1 | ENSGALP00000072284 | ENSGALP00000004697 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Beclin-1; Plays a central role in autophagy (By similarity). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways such as initiation of autophagosomes, maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Belongs to the beclin family. | 0.999 |
PIK3C3 | SH3GLB1 | ENSGALP00000072284 | ENSGALP00000047220 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | Endophilin-B1; May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion (By similarity). Belongs to the endophilin family. | 0.571 |
PIK3C3 | UVRAG | ENSGALP00000072284 | ENSGALP00000051951 | Phosphatidylinositol 3-kinase catalytic subunit type 3. | C2 domain-containing protein. | 0.996 |
SH3GLB1 | AMBRA1 | ENSGALP00000047220 | ENSGALP00000037597 | Endophilin-B1; May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion (By similarity). Belongs to the endophilin family. | Autophagy and beclin 1 regulator 1. | 0.627 |
SH3GLB1 | BCAP29 | ENSGALP00000047220 | ENSGALP00000012985 | Endophilin-B1; May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion (By similarity). Belongs to the endophilin family. | Uncharacterized protein. | 0.606 |