BCL2A1 protein (Gallus gallus) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

BCL2A1

Protein A1. (174 aa)

Predicted Functional Partners:

BCL2L11

0.975

BAK1

0.937

PMAIP1

0.928

BID

0.916

MTHFS

0.809

BMF

0.781

APAF1

0.715

BECN1

0.649

FKBP5

0.547

GPR65

0.513

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APAF1	BAK1	ENSGALP00000037437	ENSGALP00000055311	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.817
APAF1	BCL2A1	ENSGALP00000037437	ENSGALP00000010509	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Protein A1.	0.715
APAF1	BCL2L11	ENSGALP00000037437	ENSGALP00000070659	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	BCL2 like 11.	0.640
APAF1	BECN1	ENSGALP00000037437	ENSGALP00000004697	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Beclin-1; Plays a central role in autophagy (By similarity). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways such as initiation of autophagosomes, maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Belongs to the beclin family.	0.431
APAF1	BID	ENSGALP00000037437	ENSGALP00000048995	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	BH3-interacting domain death agonist; Induces caspases and apoptosis. Counters the protective effect of Bcl-2 (By similarity).	0.559
APAF1	BMF	ENSGALP00000037437	ENSGALP00000041985	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.508
APAF1	PMAIP1	ENSGALP00000037437	ENSGALP00000049825	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.417
BAK1	APAF1	ENSGALP00000055311	ENSGALP00000037437	Uncharacterized protein.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.817
BAK1	BCL2A1	ENSGALP00000055311	ENSGALP00000010509	Uncharacterized protein.	Protein A1.	0.937
BAK1	BCL2L11	ENSGALP00000055311	ENSGALP00000070659	Uncharacterized protein.	BCL2 like 11.	0.916
BAK1	BECN1	ENSGALP00000055311	ENSGALP00000004697	Uncharacterized protein.	Beclin-1; Plays a central role in autophagy (By similarity). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways such as initiation of autophagosomes, maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Belongs to the beclin family.	0.681
BAK1	BID	ENSGALP00000055311	ENSGALP00000048995	Uncharacterized protein.	BH3-interacting domain death agonist; Induces caspases and apoptosis. Counters the protective effect of Bcl-2 (By similarity).	0.995
BAK1	BMF	ENSGALP00000055311	ENSGALP00000041985	Uncharacterized protein.	Uncharacterized protein.	0.584
BAK1	PMAIP1	ENSGALP00000055311	ENSGALP00000049825	Uncharacterized protein.	Uncharacterized protein.	0.498
BCL2A1	APAF1	ENSGALP00000010509	ENSGALP00000037437	Protein A1.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.715
BCL2A1	BAK1	ENSGALP00000010509	ENSGALP00000055311	Protein A1.	Uncharacterized protein.	0.937
BCL2A1	BCL2L11	ENSGALP00000010509	ENSGALP00000070659	Protein A1.	BCL2 like 11.	0.975
BCL2A1	BECN1	ENSGALP00000010509	ENSGALP00000004697	Protein A1.	Beclin-1; Plays a central role in autophagy (By similarity). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways such as initiation of autophagosomes, maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Belongs to the beclin family.	0.649
BCL2A1	BID	ENSGALP00000010509	ENSGALP00000048995	Protein A1.	BH3-interacting domain death agonist; Induces caspases and apoptosis. Counters the protective effect of Bcl-2 (By similarity).	0.916
BCL2A1	BMF	ENSGALP00000010509	ENSGALP00000041985	Protein A1.	Uncharacterized protein.	0.781