node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |

FN1 | ILK | ENSGALP00000005653 | ENSGALP00000027964 | Fibronectin; Gallus gallus fibronectin 1 (FN1), mRNA | Integrin-linked protein kinase | 0.650 |

FN1 | ITGA2 | ENSGALP00000005653 | ENSGALP00000023991 | Fibronectin; Gallus gallus fibronectin 1 (FN1), mRNA | Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.619 |

FN1 | ITGA4 | ENSGALP00000005653 | ENSGALP00000014591 | Fibronectin; Gallus gallus fibronectin 1 (FN1), mRNA | Integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.658 |

FN1 | ITGA6 | ENSGALP00000005653 | ENSGALP00000037814 | Fibronectin; Gallus gallus fibronectin 1 (FN1), mRNA | Integrin alpha-6; Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells. It plays a critical structural role in the hemidesmosome. ITGA6-ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6-ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (By similarity) | 0.579 |

FN1 | ITGA8 | ENSGALP00000005653 | ENSGALP00000014220 | Fibronectin; Gallus gallus fibronectin 1 (FN1), mRNA | Integrin alpha-8; Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1, TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis (By similarity). Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons | 0.589 |

FN1 | ITGA9 | ENSGALP00000005653 | ENSGALP00000019958 | Fibronectin; Gallus gallus fibronectin 1 (FN1), mRNA | Gallus gallus integrin, alpha 9 (ITGA9), mRNA | 0.473 |

FN1 | ITGAD | ENSGALP00000005653 | ENSGALP00000041747 | Fibronectin; Gallus gallus fibronectin 1 (FN1), mRNA | Uncharacterized protein | 0.534 |

FN1 | ITGAV | ENSGALP00000005653 | ENSGALP00000004173 | Fibronectin; Gallus gallus fibronectin 1 (FN1), mRNA | Integrin alpha-V; The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV-ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGAV-ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV-ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV-ITGB3 binds to IGF1 and this binding is [...] | 0.871 |

FN1 | ITGB1 | ENSGALP00000005653 | ENSGALP00000011559 | Fibronectin; Gallus gallus fibronectin 1 (FN1), mRNA | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta- 1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha- 1/beta-1 and alpha-2/beta-1 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha- 3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha- 10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.990 |

FN1 | PELO | ENSGALP00000005653 | ENSGALP00000023976 | Fibronectin; Gallus gallus fibronectin 1 (FN1), mRNA | Integrin alpha-1; Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth (By similarity) | 0.506 |

ILK | FN1 | ENSGALP00000027964 | ENSGALP00000005653 | Integrin-linked protein kinase | Fibronectin; Gallus gallus fibronectin 1 (FN1), mRNA | 0.650 |

ILK | ITGA6 | ENSGALP00000027964 | ENSGALP00000037814 | Integrin-linked protein kinase | Integrin alpha-6; Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells. It plays a critical structural role in the hemidesmosome. ITGA6-ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6-ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (By similarity) | 0.462 |

ILK | ITGA8 | ENSGALP00000027964 | ENSGALP00000014220 | Integrin-linked protein kinase | Integrin alpha-8; Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1, TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis (By similarity). Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons | 0.477 |

ILK | ITGAV | ENSGALP00000027964 | ENSGALP00000004173 | Integrin-linked protein kinase | Integrin alpha-V; The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV-ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling. ITGAV-ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV-ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV-ITGB3 binds to IGF1 and this binding is [...] | 0.501 |

ILK | ITGB1 | ENSGALP00000027964 | ENSGALP00000011559 | Integrin-linked protein kinase | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta- 1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha- 1/beta-1 and alpha-2/beta-1 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha- 3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha- 10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.987 |

ITGA2 | FN1 | ENSGALP00000023991 | ENSGALP00000005653 | Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | Fibronectin; Gallus gallus fibronectin 1 (FN1), mRNA | 0.619 |

ITGA2 | ITGB1 | ENSGALP00000023991 | ENSGALP00000011559 | Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta- 1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha- 1/beta-1 and alpha-2/beta-1 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha- 3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha- 10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.973 |

ITGA4 | FN1 | ENSGALP00000014591 | ENSGALP00000005653 | Integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | Fibronectin; Gallus gallus fibronectin 1 (FN1), mRNA | 0.658 |

ITGA4 | ITGAD | ENSGALP00000014591 | ENSGALP00000041747 | Integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | Uncharacterized protein | 0.602 |

ITGA4 | ITGB1 | ENSGALP00000014591 | ENSGALP00000011559 | Integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta- 1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha- 1/beta-1 and alpha-2/beta-1 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha- 3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha- 10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] | 0.987 |