STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPRGReceptor-type tyrosine-protein phosphatase gamma; Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. (1422 aa)    
Predicted Functional Partners:
CNTN6
Contactin 6.
    
 
 0.957
CNTN4
Contactin 4.
    
 
 0.941
CNTN3
Contactin 3.
    
 
 0.921
CNTN5
Contactin-5; Contactins mediate cell surface interactions during nervous system development. May contribute to the formation of somatotopic maps of cerebellar afferents during the development of the nervous system. Belongs to the immunoglobulin superfamily. Contactin family.
    
 
 0.897
CNTN2
Contactin-2; Axon-associated cell adhesion molecule (AxCAM) which promotes neurite outgrowth by interaction with the AxCAM L1 (G4) of neuritic membrane. Contributes to the organization of axonal domains at nodes of Ranvier (By similarity).
    
 
 0.837
CNTN1
Contactin-1; Mediates cell surface interactions during nervous system development. Interaction with TNR enhances the neurite outgrowth. Belongs to the immunoglobulin superfamily. Contactin family.
    
 
 0.766
CCDC71
Coiled-coil domain containing 71.
      
 0.747
NRCAM
Neuronal cell adhesion molecule; This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Specifically involved in the development of optic fibres in the retina; Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
    
 
 0.686
GRIN3A
Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
    
 
 0.648
FSTL5
Follistatin like 5.
   
 
 0.645
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: medium (74%) [HD]