node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BPGM | CSTF3 | ENSGALP00000021309 | ENSGALP00000019081 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | Suf domain-containing protein. | 0.516 |
BPGM | ENO1 | ENSGALP00000021309 | ENSGALP00000060414 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | Alpha-enolase. | 0.981 |
BPGM | ENO2 | ENSGALP00000021309 | ENSGALP00000061472 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | Gamma-enolase; Belongs to the enolase family. | 0.982 |
BPGM | GAPDH | ENSGALP00000021309 | ENSGALP00000063325 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] | 0.968 |
BPGM | GPI | ENSGALP00000021309 | ENSGALP00000060970 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.953 |
BPGM | LOC107051217 | ENSGALP00000021309 | ENSGALP00000066789 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | Gp_dh_C domain-containing protein. | 0.636 |
BPGM | PGAM1 | ENSGALP00000021309 | ENSGALP00000038677 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | Phosphoglycerate mutase 1; Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity. | 0.906 |
BPGM | PGK2 | ENSGALP00000021309 | ENSGALP00000012878 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | Phosphoglycerate kinase; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. | 0.993 |
BPGM | PKLR | ENSGALP00000021309 | ENSGALP00000049508 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | Pyruvate kinase PKM; Plays a key role in glycolysis; Belongs to the pyruvate kinase family. | 0.762 |
BPGM | TPI1 | ENSGALP00000021309 | ENSGALP00000023396 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. | 0.965 |
CSTF3 | BPGM | ENSGALP00000019081 | ENSGALP00000021309 | Suf domain-containing protein. | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 0.516 |
CSTF3 | ENO1 | ENSGALP00000019081 | ENSGALP00000060414 | Suf domain-containing protein. | Alpha-enolase. | 0.925 |
CSTF3 | ENO2 | ENSGALP00000019081 | ENSGALP00000061472 | Suf domain-containing protein. | Gamma-enolase; Belongs to the enolase family. | 0.924 |
CSTF3 | GAPDH | ENSGALP00000019081 | ENSGALP00000063325 | Suf domain-containing protein. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] | 0.739 |
CSTF3 | GPI | ENSGALP00000019081 | ENSGALP00000060970 | Suf domain-containing protein. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.769 |
CSTF3 | LOC107051217 | ENSGALP00000019081 | ENSGALP00000066789 | Suf domain-containing protein. | Gp_dh_C domain-containing protein. | 0.739 |
CSTF3 | PGAM1 | ENSGALP00000019081 | ENSGALP00000038677 | Suf domain-containing protein. | Phosphoglycerate mutase 1; Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase), but with a reduced activity. | 0.501 |
CSTF3 | PGK2 | ENSGALP00000019081 | ENSGALP00000012878 | Suf domain-containing protein. | Phosphoglycerate kinase; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. | 0.973 |
CSTF3 | PKLR | ENSGALP00000019081 | ENSGALP00000049508 | Suf domain-containing protein. | Pyruvate kinase PKM; Plays a key role in glycolysis; Belongs to the pyruvate kinase family. | 0.642 |
CSTF3 | TPI1 | ENSGALP00000019081 | ENSGALP00000023396 | Suf domain-containing protein. | Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. | 0.993 |