STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM237Transmembrane protein 237; Component of the transition zone in primary cilia. Required for ciliogenesis (By similarity); Belongs to the TMEM237 family. (400 aa)    
Predicted Functional Partners:
TMEM231
Transmembrane protein 231; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
      
 0.960
TMEM17
Transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
   
  
 0.923
NPHP1
SH3 domain-containing protein.
   
 
 0.910
RPGRIP1L
RPGRIP1 like.
    
 
 0.906
TCTN1
Tectonic family member 1.
   
  
 0.903
NPHP4
Nephrocystin 4.
      
 0.878
B9D1
B9 domain containing 1.
      
 0.876
TMEM107
Uncharacterized protein.
   
 
 0.874
CC2D2A
Coiled-coil and C2 domain containing 2A.
   
  
 0.869
TMEM67
Transmembrane protein 67.
   
  
 0.865
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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