STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CACNA1BVoltage-dependent N-type calcium channel subunit alpha-1B; The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons (By similarity). (2357 aa)    
Predicted Functional Partners:
CACNA1E
Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.
  
 
0.954
CACNB2
Calcium voltage-gated channel auxiliary subunit beta 2.
   
 0.918
CACNA2D1
VWFA domain-containing protein.
   
 0.916
CACNB4
SH3 domain-containing protein.
   
 0.908
CACNA2D2
Calcium voltage-gated channel auxiliary subunit alpha2delta 2.
   
 0.894
CACNA2D3
Calcium voltage-gated channel auxiliary subunit alpha2delta 3.
   
 0.881
CACNB3
Calcium voltage-gated channel auxiliary subunit beta 3.
   
 0.869
CACNB1
Calcium voltage-gated channel auxiliary subunit beta 1.
   
 0.844
CACNA2D4
VWFA domain-containing protein.
   
 0.842
STX1A
Syntaxin 1A; Belongs to the syntaxin family.
    
 
 0.807
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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