STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCSK2Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family. (644 aa)    
Predicted Functional Partners:
CPE
Carboxypeptidase E.
   
  
 0.844
SCG5
Uncharacterized protein.
   
 
 0.825
PTPRN
Protein tyrosine phosphatase receptor type N.
   
  
 0.681
BSND
Uncharacterized protein.
      
 0.671
PTPRN2
Protein tyrosine phosphatase receptor type N2.
   
  
 0.657
CNTN2
Contactin-2; Axon-associated cell adhesion molecule (AxCAM) which promotes neurite outgrowth by interaction with the AxCAM L1 (G4) of neuritic membrane. Contributes to the organization of axonal domains at nodes of Ranvier (By similarity).
   
  
 0.632
SLC2A2
Solute carrier family 2, facilitated glucose transporter member 2; Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. Also able to mediate the transport of dehydroascorbate.
      
 0.585
USP24
Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family.
      
 0.581
SST
Somatostatin-14; Somatostatin inhibits the release of somatotropin.
   
  
 0.573
NPSR1
Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
      
 0.571
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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