CTSO protein (Gallus gallus) - STRING interaction network

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Predicted Interactions

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Score

CTSO

Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (320 aa)

Predicted Functional Partners:

BCL2

0.901

BCL2L1

0.901

BID

0.900

LGMN

0.818

ESPL1

0.699

BIRC3

0.660

BIRC5

0.660

LOC768589

0.660

BIRC8

0.660

BCS1L

0.628

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2	BCL2L1	ENSGALP00000020984	ENSGALP00000054103	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).	Bcl-2-like protein 1; Dominant regulator of apoptotic cell death. The long form displays cell death repressor activity, whereas the short isoform promotes apoptosis. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis (By similarity).	0.972
BCL2	BID	ENSGALP00000020984	ENSGALP00000048995	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).	BH3-interacting domain death agonist; Induces caspases and apoptosis. Counters the protective effect of Bcl-2 (By similarity).	0.989
BCL2	BIRC3	ENSGALP00000020984	ENSGALP00000035646	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).	Inhibitor of apoptosis protein; Apoptotic suppressor.	0.626
BCL2	BIRC5	ENSGALP00000020984	ENSGALP00000038330	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).	Uncharacterized protein.	0.426
BCL2	BIRC8	ENSGALP00000020984	ENSGALP00000073811	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).	Inhibitor of apoptosis protein 3.	0.906
BCL2	CTSO	ENSGALP00000020984	ENSGALP00000015254	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.901
BCL2L1	BCL2	ENSGALP00000054103	ENSGALP00000020984	Bcl-2-like protein 1; Dominant regulator of apoptotic cell death. The long form displays cell death repressor activity, whereas the short isoform promotes apoptosis. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis (By similarity).	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).	0.972
BCL2L1	BID	ENSGALP00000054103	ENSGALP00000048995	Bcl-2-like protein 1; Dominant regulator of apoptotic cell death. The long form displays cell death repressor activity, whereas the short isoform promotes apoptosis. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis (By similarity).	BH3-interacting domain death agonist; Induces caspases and apoptosis. Counters the protective effect of Bcl-2 (By similarity).	0.979
BCL2L1	BIRC3	ENSGALP00000054103	ENSGALP00000035646	Bcl-2-like protein 1; Dominant regulator of apoptotic cell death. The long form displays cell death repressor activity, whereas the short isoform promotes apoptosis. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis (By similarity).	Inhibitor of apoptosis protein; Apoptotic suppressor.	0.653
BCL2L1	BIRC8	ENSGALP00000054103	ENSGALP00000073811	Bcl-2-like protein 1; Dominant regulator of apoptotic cell death. The long form displays cell death repressor activity, whereas the short isoform promotes apoptosis. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis (By similarity).	Inhibitor of apoptosis protein 3.	0.917
BCL2L1	CTSO	ENSGALP00000054103	ENSGALP00000015254	Bcl-2-like protein 1; Dominant regulator of apoptotic cell death. The long form displays cell death repressor activity, whereas the short isoform promotes apoptosis. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis (By similarity).	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.901
BCS1L	CTSO	ENSGALP00000064039	ENSGALP00000015254	Uncharacterized protein; Belongs to the AAA ATPase family.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.628
BID	BCL2	ENSGALP00000048995	ENSGALP00000020984	BH3-interacting domain death agonist; Induces caspases and apoptosis. Counters the protective effect of Bcl-2 (By similarity).	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).	0.989
BID	BCL2L1	ENSGALP00000048995	ENSGALP00000054103	BH3-interacting domain death agonist; Induces caspases and apoptosis. Counters the protective effect of Bcl-2 (By similarity).	Bcl-2-like protein 1; Dominant regulator of apoptotic cell death. The long form displays cell death repressor activity, whereas the short isoform promotes apoptosis. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis (By similarity).	0.979
BID	CTSO	ENSGALP00000048995	ENSGALP00000015254	BH3-interacting domain death agonist; Induces caspases and apoptosis. Counters the protective effect of Bcl-2 (By similarity).	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.900
BIRC3	BCL2	ENSGALP00000035646	ENSGALP00000020984	Inhibitor of apoptosis protein; Apoptotic suppressor.	Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).	0.626
BIRC3	BCL2L1	ENSGALP00000035646	ENSGALP00000054103	Inhibitor of apoptosis protein; Apoptotic suppressor.	Bcl-2-like protein 1; Dominant regulator of apoptotic cell death. The long form displays cell death repressor activity, whereas the short isoform promotes apoptosis. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis (By similarity).	0.653
BIRC3	BIRC5	ENSGALP00000035646	ENSGALP00000038330	Inhibitor of apoptosis protein; Apoptotic suppressor.	Uncharacterized protein.	0.406
BIRC3	BIRC8	ENSGALP00000035646	ENSGALP00000073811	Inhibitor of apoptosis protein; Apoptotic suppressor.	Inhibitor of apoptosis protein 3.	0.968
BIRC3	CTSO	ENSGALP00000035646	ENSGALP00000015254	Inhibitor of apoptosis protein; Apoptotic suppressor.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.660