node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRAF | RAP1A | ENSGALP00000020950 | ENSGALP00000002236 | Serine/threonine-protein kinase B-raf; Protein kinase involved in the activation of the MAP signaling cascade. May play a role in transducing specific signals in neural cells; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. | 0.967 |
BRAF | RAP1B | ENSGALP00000020950 | ENSGALP00000070773 | Serine/threonine-protein kinase B-raf; Protein kinase involved in the activation of the MAP signaling cascade. May play a role in transducing specific signals in neural cells; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | Ras-related protein Rap-1b. | 0.963 |
BRAF | RGL4 | ENSGALP00000020950 | ENSGALP00000005387 | Serine/threonine-protein kinase B-raf; Protein kinase involved in the activation of the MAP signaling cascade. May play a role in transducing specific signals in neural cells; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | Uncharacterized protein. | 0.612 |
KRIT1 | RAP1A | ENSGALP00000052196 | ENSGALP00000002236 | Uncharacterized protein. | Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. | 0.693 |
KRIT1 | RAP1B | ENSGALP00000052196 | ENSGALP00000070773 | Uncharacterized protein. | Ras-related protein Rap-1b. | 0.687 |
MAPK10 | MAPK8 | ENSGALP00000057620 | ENSGALP00000066941 | Mitogen-activated protein kinase. | Mitogen-activated protein kinase. | 0.900 |
MAPK10 | MAPK9 | ENSGALP00000057620 | ENSGALP00000072370 | Mitogen-activated protein kinase. | Mitogen-activated protein kinase 9; Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity (By similarity). May play a role in the development of the central nervous system during embryogenesis. May play a role in the regulation of the circadian clock (By similarity); Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. | 0.984 |
MAPK10 | RAP1A | ENSGALP00000057620 | ENSGALP00000002236 | Mitogen-activated protein kinase. | Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. | 0.914 |
MAPK10 | RAP1B | ENSGALP00000057620 | ENSGALP00000070773 | Mitogen-activated protein kinase. | Ras-related protein Rap-1b. | 0.914 |
MAPK8 | MAPK10 | ENSGALP00000066941 | ENSGALP00000057620 | Mitogen-activated protein kinase. | Mitogen-activated protein kinase. | 0.900 |
MAPK8 | MAPK9 | ENSGALP00000066941 | ENSGALP00000072370 | Mitogen-activated protein kinase. | Mitogen-activated protein kinase 9; Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity (By similarity). May play a role in the development of the central nervous system during embryogenesis. May play a role in the regulation of the circadian clock (By similarity); Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. | 0.984 |
MAPK8 | RAP1A | ENSGALP00000066941 | ENSGALP00000002236 | Mitogen-activated protein kinase. | Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. | 0.914 |
MAPK8 | RAP1B | ENSGALP00000066941 | ENSGALP00000070773 | Mitogen-activated protein kinase. | Ras-related protein Rap-1b. | 0.915 |
MAPK9 | MAPK10 | ENSGALP00000072370 | ENSGALP00000057620 | Mitogen-activated protein kinase 9; Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity (By similarity). May play a role in the development of the central nervous system during embryogenesis. May play a role in the regulation of the circadian clock (By similarity); Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. | Mitogen-activated protein kinase. | 0.984 |
MAPK9 | MAPK8 | ENSGALP00000072370 | ENSGALP00000066941 | Mitogen-activated protein kinase 9; Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity (By similarity). May play a role in the development of the central nervous system during embryogenesis. May play a role in the regulation of the circadian clock (By similarity); Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. | Mitogen-activated protein kinase. | 0.984 |
MAPK9 | RAP1A | ENSGALP00000072370 | ENSGALP00000002236 | Mitogen-activated protein kinase 9; Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity (By similarity). May play a role in the development of the central nervous system during embryogenesis. May play a role in the regulation of the circadian clock (By similarity); Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. | Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. | 0.916 |
MAPK9 | RAP1B | ENSGALP00000072370 | ENSGALP00000070773 | Mitogen-activated protein kinase 9; Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity (By similarity). May play a role in the development of the central nervous system during embryogenesis. May play a role in the regulation of the circadian clock (By similarity); Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. | Ras-related protein Rap-1b. | 0.914 |
PRKACB | RAP1A | ENSGALP00000041979 | ENSGALP00000002236 | Uncharacterized protein; Belongs to the protein kinase superfamily. | Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. | 0.934 |
PRKACB | RAP1B | ENSGALP00000041979 | ENSGALP00000070773 | Uncharacterized protein; Belongs to the protein kinase superfamily. | Ras-related protein Rap-1b. | 0.924 |
RAP1A | BRAF | ENSGALP00000002236 | ENSGALP00000020950 | Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. | Serine/threonine-protein kinase B-raf; Protein kinase involved in the activation of the MAP signaling cascade. May play a role in transducing specific signals in neural cells; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. | 0.967 |