Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AIP | HSP90AB1 | ENSGALP00000055298 | ENSGALP00000016523 | Aryl-hydrocarbon receptor-interacting protein. | Heat shock cognate protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its [...] | 0.921 |
| AIP | HSP90B1 | ENSGALP00000055298 | ENSGALP00000054843 | Aryl-hydrocarbon receptor-interacting protein. | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). Has ATPase activity (By similarity). | 0.454 |
| AIP | PTGES3 | ENSGALP00000055298 | ENSGALP00000069892 | Aryl-hydrocarbon receptor-interacting protein. | Prostaglandin E synthase 3; Molecular chaperone. | 0.909 |
| CDC37 | FKBP5 | ENSGALP00000072245 | ENSGALP00000067232 | Hsp90 co-chaperone Cdc37; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. | Peptidylprolyl isomerase. | 0.615 |
| CDC37 | HSP90AB1 | ENSGALP00000072245 | ENSGALP00000016523 | Hsp90 co-chaperone Cdc37; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. | Heat shock cognate protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its [...] | 0.951 |
| CDC37 | HSP90B1 | ENSGALP00000072245 | ENSGALP00000054843 | Hsp90 co-chaperone Cdc37; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). Has ATPase activity (By similarity). | 0.735 |
| CDC37 | HSPA8 | ENSGALP00000072245 | ENSGALP00000051563 | Hsp90 co-chaperone Cdc37; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. | Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...] | 0.414 |
| CDC37 | MLKL | ENSGALP00000072245 | ENSGALP00000004360 | Hsp90 co-chaperone Cdc37; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. | Mixed lineage kinase domain like pseudokinase. | 0.617 |
| CDC37 | PTGES3 | ENSGALP00000072245 | ENSGALP00000069892 | Hsp90 co-chaperone Cdc37; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. | Prostaglandin E synthase 3; Molecular chaperone. | 0.778 |
| CDC37 | STIP1 | ENSGALP00000072245 | ENSGALP00000066776 | Hsp90 co-chaperone Cdc37; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. | Stress induced phosphoprotein 1. | 0.828 |
| FKBP5 | CDC37 | ENSGALP00000067232 | ENSGALP00000072245 | Peptidylprolyl isomerase. | Hsp90 co-chaperone Cdc37; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. | 0.615 |
| FKBP5 | HSP90AB1 | ENSGALP00000067232 | ENSGALP00000016523 | Peptidylprolyl isomerase. | Heat shock cognate protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its [...] | 0.920 |
| FKBP5 | HSPA8 | ENSGALP00000067232 | ENSGALP00000051563 | Peptidylprolyl isomerase. | Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...] | 0.770 |
| FKBP5 | PTGES3 | ENSGALP00000067232 | ENSGALP00000069892 | Peptidylprolyl isomerase. | Prostaglandin E synthase 3; Molecular chaperone. | 0.949 |
| FKBP5 | STIP1 | ENSGALP00000067232 | ENSGALP00000066776 | Peptidylprolyl isomerase. | Stress induced phosphoprotein 1. | 0.794 |
| FKBP5 | SUGT1 | ENSGALP00000067232 | ENSGALP00000035717 | Peptidylprolyl isomerase. | Uncharacterized protein. | 0.410 |
| HSP90AB1 | AIP | ENSGALP00000016523 | ENSGALP00000055298 | Heat shock cognate protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its [...] | Aryl-hydrocarbon receptor-interacting protein. | 0.921 |
| HSP90AB1 | CDC37 | ENSGALP00000016523 | ENSGALP00000072245 | Heat shock cognate protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its [...] | Hsp90 co-chaperone Cdc37; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. | 0.951 |
| HSP90AB1 | FKBP5 | ENSGALP00000016523 | ENSGALP00000067232 | Heat shock cognate protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its [...] | Peptidylprolyl isomerase. | 0.920 |
| HSP90AB1 | HSP90B1 | ENSGALP00000016523 | ENSGALP00000054843 | Heat shock cognate protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its [...] | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). Has ATPase activity (By similarity). | 0.929 |
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