STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DAZLDeleted in azoospermia-like; RNA-binding protein, which probably plays a central role in gametogenesis in both males and females. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and promoting the translation of key transcripts (By similarity); Belongs to the RRM DAZ family. (289 aa)    
Predicted Functional Partners:
STRA8
Stimulated by retinoic acid 8.
   
  
 0.937
DDX4
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
 
 0.898
DND1
DND microRNA-mediated repression inhibitor 1.
   
 
 0.890
SYCP3
Cor1 domain-containing protein.
    
 
 0.856
NPDC1
POU domain, class 5, transcription factor 3; Required for the maintenance of pluripotency and self-renewal of embryonic stem cells. Transcriptional activator that binds the DNA consensus sequence 5'-ATGCAAAT-3'; Belongs to the POU transcription factor family.
    
 
 0.850
PIWIL1
Piwi-like protein 1; Endoribonuclease that plays a central role in postnatal germ cells by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived fro [...]
   
 
 0.827
PRDM14
PR/SET domain 14.
    
 
 0.802
ZBTB32
Uncharacterized protein.
   
 
 0.750
TDRD9-2
Uncharacterized protein.
   
 
 0.742
TDRD9
Tudor domain containing 9.
   
 
 0.737
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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