node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTB | AFDN | ENSGALP00000060844 | ENSGALP00000049197 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Afadin, adherens junction formation factor. | 0.995 |
ACTB | CTNNA2 | ENSGALP00000060844 | ENSGALP00000025681 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. | 0.942 |
ACTB | CTNNA3 | ENSGALP00000060844 | ENSGALP00000073087 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Uncharacterized protein. | 0.925 |
ACTB | TJP1 | ENSGALP00000060844 | ENSGALP00000044872 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Tight junction protein 1; Belongs to the MAGUK family. | 0.961 |
ACTB | TJP2 | ENSGALP00000060844 | ENSGALP00000049244 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Uncharacterized protein; Belongs to the MAGUK family. | 0.701 |
AFDN | ACTB | ENSGALP00000049197 | ENSGALP00000060844 | Afadin, adherens junction formation factor. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.995 |
AFDN | CTNNA2 | ENSGALP00000049197 | ENSGALP00000025681 | Afadin, adherens junction formation factor. | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. | 0.965 |
AFDN | CTNNA3 | ENSGALP00000049197 | ENSGALP00000073087 | Afadin, adherens junction formation factor. | Uncharacterized protein. | 0.942 |
AFDN | LMO7 | ENSGALP00000049197 | ENSGALP00000027304 | Afadin, adherens junction formation factor. | LIM domain 7. | 0.962 |
AFDN | NECTIN1 | ENSGALP00000049197 | ENSGALP00000057900 | Afadin, adherens junction formation factor. | Nectin cell adhesion molecule 1. | 0.986 |
AFDN | NECTIN3 | ENSGALP00000049197 | ENSGALP00000024751 | Afadin, adherens junction formation factor. | Nectin cell adhesion molecule 3. | 0.995 |
AFDN | NECTIN4 | ENSGALP00000049197 | ENSGALP00000065817 | Afadin, adherens junction formation factor. | Nectin cell adhesion molecule 4. | 0.962 |
AFDN | RAP1A | ENSGALP00000049197 | ENSGALP00000002236 | Afadin, adherens junction formation factor. | Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. | 0.953 |
AFDN | TJP1 | ENSGALP00000049197 | ENSGALP00000044872 | Afadin, adherens junction formation factor. | Tight junction protein 1; Belongs to the MAGUK family. | 0.984 |
AFDN | TJP2 | ENSGALP00000049197 | ENSGALP00000049244 | Afadin, adherens junction formation factor. | Uncharacterized protein; Belongs to the MAGUK family. | 0.993 |
CTNNA2 | ACTB | ENSGALP00000025681 | ENSGALP00000060844 | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.942 |
CTNNA2 | AFDN | ENSGALP00000025681 | ENSGALP00000049197 | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. | Afadin, adherens junction formation factor. | 0.965 |
CTNNA2 | CTNNA3 | ENSGALP00000025681 | ENSGALP00000073087 | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. | Uncharacterized protein. | 0.903 |
CTNNA2 | TJP1 | ENSGALP00000025681 | ENSGALP00000044872 | Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. | Tight junction protein 1; Belongs to the MAGUK family. | 0.918 |
CTNNA3 | ACTB | ENSGALP00000073087 | ENSGALP00000060844 | Uncharacterized protein. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.925 |