node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C16orf96 | GLB1L | ENSGALP00000071546 | ENSGALP00000018459 | Uncharacterized protein. | Galactosidase beta 1 like; Belongs to the glycosyl hydrolase 35 family. | 0.866 |
C16orf96 | SLC11A1 | ENSGALP00000071546 | ENSGALP00000018625 | Uncharacterized protein. | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] | 0.609 |
FECH | H6PD | ENSGALP00000043525 | ENSGALP00000003917 | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family. | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. | 0.648 |
FECH | SLC11A1 | ENSGALP00000043525 | ENSGALP00000018625 | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family. | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] | 0.652 |
FECH | SLC11A2 | ENSGALP00000043525 | ENSGALP00000069122 | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family. | Uncharacterized protein. | 0.698 |
GLB1L | C16orf96 | ENSGALP00000018459 | ENSGALP00000071546 | Galactosidase beta 1 like; Belongs to the glycosyl hydrolase 35 family. | Uncharacterized protein. | 0.866 |
GLB1L | SLC11A1 | ENSGALP00000018459 | ENSGALP00000018625 | Galactosidase beta 1 like; Belongs to the glycosyl hydrolase 35 family. | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] | 0.514 |
H6PD | FECH | ENSGALP00000003917 | ENSGALP00000043525 | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family. | 0.648 |
H6PD | SLC11A1 | ENSGALP00000003917 | ENSGALP00000018625 | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] | 0.520 |
H6PD | SLC11A2 | ENSGALP00000003917 | ENSGALP00000069122 | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. | Uncharacterized protein. | 0.471 |
PAF1 | SLC11A1 | ENSGALP00000046348 | ENSGALP00000018625 | PAF1 homolog, Paf1/RNA polymerase II complex component. | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] | 0.533 |
SLC11A1 | C16orf96 | ENSGALP00000018625 | ENSGALP00000071546 | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] | Uncharacterized protein. | 0.609 |
SLC11A1 | FECH | ENSGALP00000018625 | ENSGALP00000043525 | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] | Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family. | 0.652 |
SLC11A1 | GLB1L | ENSGALP00000018625 | ENSGALP00000018459 | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] | Galactosidase beta 1 like; Belongs to the glycosyl hydrolase 35 family. | 0.514 |
SLC11A1 | H6PD | ENSGALP00000018625 | ENSGALP00000003917 | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. | 0.520 |
SLC11A1 | PAF1 | ENSGALP00000018625 | ENSGALP00000046348 | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] | PAF1 homolog, Paf1/RNA polymerase II complex component. | 0.533 |
SLC11A1 | SLC11A2 | ENSGALP00000018625 | ENSGALP00000069122 | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] | Uncharacterized protein. | 0.904 |
SLC11A1 | SLC30A9 | ENSGALP00000018625 | ENSGALP00000044437 | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] | Solute carrier family 30 member 9. | 0.656 |
SLC11A1 | SLC40A1 | ENSGALP00000018625 | ENSGALP00000045816 | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] | Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. | 0.555 |
SLC11A1 | SPI1 | ENSGALP00000018625 | ENSGALP00000047958 | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] | ETS domain-containing protein. | 0.632 |