STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBXTT-box transcription factor T; Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site. (433 aa)    
Predicted Functional Partners:
MSRB3
Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.
      
 0.692
RNF145
Ring finger protein 145.
      
 0.583
DNAJB5
DnaJ heat shock protein family (Hsp40) member B5.
   
  
 0.582
FOXA2
Fork-head domain-containing protein.
    
 
 0.541
SOX17
Uncharacterized protein.
    
 
 0.538
TFAP2A
TF_AP-2 domain-containing protein.
   
 
 0.489
RIN3
Ras and Rab interactor 3.
      
 0.483
PRPH
Peripherin; Belongs to the intermediate filament family.
      
 0.482
THNSL2
Threonine synthase like 2.
      
 0.481
CDX4
Homeobox protein CHOX-CAD2; Belongs to the Caudal homeobox family.
   
 
 0.465
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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