STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCS1Neuronal calcium sensor 1. (265 aa)    
Predicted Functional Partners:
DRD2
Dopamine receptor 2 protein transcript variant 1; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.907
PI4KB
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
    
 
 0.847
IL1RAPL1
Interleukin 1 receptor accessory protein like 1.
   
 
 0.645
DRD3
Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.624
SLC44A5
Solute carrier family 44 member 5; Belongs to the CTL (choline transporter-like) family.
   
  
 0.601
RIC8A
Synembryn-A; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity).
    
 
 0.566
CABP1
Calcium binding protein 1.
    
 
 0.557
DRD4
Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.546
DPP8
Dipeptidyl peptidase 8; Belongs to the peptidase S9B family.
      
 0.531
GRK1
Uncharacterized protein.
    
 
 0.529
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.