node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTB | GFAP | ENSGALP00000060844 | ENSGALP00000001335 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Glial fibrillary acidic protein; Belongs to the intermediate filament family. | 0.854 |
ACTB | MBP | ENSGALP00000060844 | ENSGALP00000065604 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). | 0.841 |
ACTB | MOG | ENSGALP00000060844 | ENSGALP00000062108 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Ig-like domain-containing protein. | 0.421 |
ACTB | OLIG2 | ENSGALP00000060844 | ENSGALP00000047462 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Oligodendrocyte transcription factor 2; Required for oligodendrocyte and motor neuron specification in the spinal cord. | 0.666 |
ACTB | PDGFRA | ENSGALP00000060844 | ENSGALP00000064586 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. Required for normal development of the gastrointestinal tract. Plays a role in cell migration and chemotaxis in wound he [...] | 0.706 |
ACTB | PXDNL | ENSGALP00000060844 | ENSGALP00000049777 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Uncharacterized protein. | 0.980 |
ACTB | SOX10 | ENSGALP00000060844 | ENSGALP00000020056 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. | 0.719 |
CNP | GALC | ENSGALP00000053616 | ENSGALP00000017218 | Uncharacterized protein. | Galactosylceramidase. | 0.675 |
CNP | GFAP | ENSGALP00000053616 | ENSGALP00000001335 | Uncharacterized protein. | Glial fibrillary acidic protein; Belongs to the intermediate filament family. | 0.731 |
CNP | MBP | ENSGALP00000053616 | ENSGALP00000065604 | Uncharacterized protein. | Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). | 0.914 |
CNP | MOG | ENSGALP00000053616 | ENSGALP00000062108 | Uncharacterized protein. | Ig-like domain-containing protein. | 0.602 |
CNP | OLIG2 | ENSGALP00000053616 | ENSGALP00000047462 | Uncharacterized protein. | Oligodendrocyte transcription factor 2; Required for oligodendrocyte and motor neuron specification in the spinal cord. | 0.721 |
CNP | PDGFRA | ENSGALP00000053616 | ENSGALP00000064586 | Uncharacterized protein. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. Required for normal development of the gastrointestinal tract. Plays a role in cell migration and chemotaxis in wound he [...] | 0.750 |
CNP | PLP1 | ENSGALP00000053616 | ENSGALP00000000160 | Uncharacterized protein. | Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin; Belongs to the myelin proteolipid protein family. | 0.718 |
CNP | SOX10 | ENSGALP00000053616 | ENSGALP00000020056 | Uncharacterized protein. | Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. | 0.519 |
GALC | CNP | ENSGALP00000017218 | ENSGALP00000053616 | Galactosylceramidase. | Uncharacterized protein. | 0.675 |
GALC | GFAP | ENSGALP00000017218 | ENSGALP00000001335 | Galactosylceramidase. | Glial fibrillary acidic protein; Belongs to the intermediate filament family. | 0.734 |
GALC | MBP | ENSGALP00000017218 | ENSGALP00000065604 | Galactosylceramidase. | Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). | 0.773 |
GALC | MOG | ENSGALP00000017218 | ENSGALP00000062108 | Galactosylceramidase. | Ig-like domain-containing protein. | 0.448 |
GALC | OLIG2 | ENSGALP00000017218 | ENSGALP00000047462 | Galactosylceramidase. | Oligodendrocyte transcription factor 2; Required for oligodendrocyte and motor neuron specification in the spinal cord. | 0.706 |