STRINGSTRING
FYN protein (Gallus gallus) - STRING interaction network
"FYN" - Tyrosine-protein kinase Fyn in Gallus gallus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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FYNTyrosine-protein kinase Fyn; Tyrosine-protein kinase implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Role in CNTN1-mediated signaling (534 aa)    
Predicted Functional Partners:
SRC
Proto-oncogene tyrosine-protein kinase Src; Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein- coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy be [...] (533 aa)
   
 
0.996
YES1
Tyrosine-protein kinase Yes; Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, differentiation, G2/M progression and cytokinesis (541 aa)
       
0.996
GRIN2B
Uncharacterized protein; Glutamate receptor, ionotropic, N-methyl D-aspartate 2B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family (1504 aa)
     
  0.987
CTNNB1
Catenin beta 1; Gallus gallus catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), mRNA (781 aa)
       
  0.983
LCP2
Gallus gallus lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) (LCP2), mRNA (530 aa)
     
  0.982
PTPN11
Tyrosine-protein phosphatase non-receptor type 11; This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates (By similarity). May play a positive role during the stages of erythroid cell proliferation (593 aa)
     
  0.981
CTNND1
Uncharacterized protein (597 aa)
     
  0.979
HRAS
GTPase HRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family (189 aa)
     
  0.978
GRIN1
Gallus gallus glutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1), mRNA (949 aa)
     
  0.978
KRAS
KRAS proto-oncogene, GTPase; Gallus gallus v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS), mRNA (188 aa)
     
  0.975
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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