Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CARD9 | FCER1G | ENSGALP00000002921 | ENSGALP00000069415 | Caspase recruitment domain family member 9. | Uncharacterized protein. | 0.429 |
CARD9 | SYK | ENSGALP00000002921 | ENSGALP00000024509 | Caspase recruitment domain family member 9. | Tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can a [...] | 0.988 |
CBLB | LCP2 | ENSGALP00000024726 | ENSGALP00000003296 | Cbl proto-oncogene B. | SH2 domain-containing protein. | 0.407 |
CBLB | SRC | ENSGALP00000024726 | ENSGALP00000006117 | Cbl proto-oncogene B. | Proto-oncogene tyrosine-protein kinase Src; Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy bet [...] | 0.464 |
CBLB | SYK | ENSGALP00000024726 | ENSGALP00000024509 | Cbl proto-oncogene B. | Tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can a [...] | 0.959 |
CD247 | CD79B | ENSGALP00000024859 | ENSGALP00000000329 | Uncharacterized protein. | B29/Ig-b. | 0.604 |
CD247 | FCER1G | ENSGALP00000024859 | ENSGALP00000069415 | Uncharacterized protein. | Uncharacterized protein. | 0.667 |
CD247 | LCP2 | ENSGALP00000024859 | ENSGALP00000003296 | Uncharacterized protein. | SH2 domain-containing protein. | 0.779 |
CD247 | PLCG2 | ENSGALP00000024859 | ENSGALP00000052324 | Uncharacterized protein. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. | 0.558 |
CD247 | PTPN11 | ENSGALP00000024859 | ENSGALP00000007692 | Uncharacterized protein. | Tyrosine-protein phosphatase non-receptor type 11; This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates (By similarity). May play a positive role during the stages of erythroid cell proliferation. | 0.580 |
CD247 | SH2D6 | ENSGALP00000024859 | ENSGALP00000070495 | Uncharacterized protein. | B-cell linker protein; Functions as a central linker protein, downstream of the B- cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR- mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-medi [...] | 0.415 |
CD247 | SRC | ENSGALP00000024859 | ENSGALP00000006117 | Uncharacterized protein. | Proto-oncogene tyrosine-protein kinase Src; Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy bet [...] | 0.652 |
CD247 | SYK | ENSGALP00000024859 | ENSGALP00000024509 | Uncharacterized protein. | Tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can a [...] | 0.957 |
CD79B | CD247 | ENSGALP00000000329 | ENSGALP00000024859 | B29/Ig-b. | Uncharacterized protein. | 0.604 |
CD79B | PLCG2 | ENSGALP00000000329 | ENSGALP00000052324 | B29/Ig-b. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. | 0.770 |
CD79B | SH2D6 | ENSGALP00000000329 | ENSGALP00000070495 | B29/Ig-b. | B-cell linker protein; Functions as a central linker protein, downstream of the B- cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR- mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-medi [...] | 0.892 |
CD79B | SYK | ENSGALP00000000329 | ENSGALP00000024509 | B29/Ig-b. | Tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can a [...] | 0.946 |
FCER1G | CARD9 | ENSGALP00000069415 | ENSGALP00000002921 | Uncharacterized protein. | Caspase recruitment domain family member 9. | 0.429 |
FCER1G | CD247 | ENSGALP00000069415 | ENSGALP00000024859 | Uncharacterized protein. | Uncharacterized protein. | 0.667 |
FCER1G | LCP2 | ENSGALP00000069415 | ENSGALP00000003296 | Uncharacterized protein. | SH2 domain-containing protein. | 0.406 |
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