node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
H2BE1 | HIST1H2B5 | ENSGALP00000057898 | ENSGALP00000069619 | Histone H2B; Belongs to the histone H2B family. | Histone H2B 5; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.409 |
H2BE1 | HIST1H2B5L | ENSGALP00000057898 | ENSGALP00000069556 | Histone H2B; Belongs to the histone H2B family. | Histone H2B; Belongs to the histone H2B family. | 0.409 |
H2BE1 | HIST1H2B8 | ENSGALP00000057898 | ENSGALP00000056960 | Histone H2B; Belongs to the histone H2B family. | Histone H2B 8; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.409 |
H2BE1 | HIST1H2BO | ENSGALP00000057898 | ENSGALP00000042437 | Histone H2B; Belongs to the histone H2B family. | Histone H2B 1/2/3/4/6; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.409 |
H2BE1 | LOC107053803 | ENSGALP00000057898 | ENSGALP00000055900 | Histone H2B; Belongs to the histone H2B family. | Histone H2B 7; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.409 |
H2BE1 | RNF20 | ENSGALP00000057898 | ENSGALP00000073707 | Histone H2B; Belongs to the histone H2B family. | E3 ubiquitin-protein ligase BRE1A; Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). | 0.808 |
H2BE1 | SETD2 | ENSGALP00000057898 | ENSGALP00000068801 | Histone H2B; Belongs to the histone H2B family. | SET domain containing 2, histone lysine methyltransferase. | 0.492 |
H2BE1 | USP22 | ENSGALP00000057898 | ENSGALP00000056329 | Histone H2B; Belongs to the histone H2B family. | Ubiquitin carboxyl-terminal hydrolase. | 0.479 |
HIST1H2B5 | H2BE1 | ENSGALP00000069619 | ENSGALP00000057898 | Histone H2B 5; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone H2B; Belongs to the histone H2B family. | 0.409 |
HIST1H2B5 | HIST1H2B5L | ENSGALP00000069619 | ENSGALP00000069556 | Histone H2B 5; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone H2B; Belongs to the histone H2B family. | 0.405 |
HIST1H2B5 | HIST1H2B8 | ENSGALP00000069619 | ENSGALP00000056960 | Histone H2B 5; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone H2B 8; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.408 |
HIST1H2B5 | HIST1H2BO | ENSGALP00000069619 | ENSGALP00000042437 | Histone H2B 5; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone H2B 1/2/3/4/6; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.803 |
HIST1H2B5 | LOC107053803 | ENSGALP00000069619 | ENSGALP00000055900 | Histone H2B 5; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone H2B 7; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.404 |
HIST1H2B5 | RNF20 | ENSGALP00000069619 | ENSGALP00000073707 | Histone H2B 5; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | E3 ubiquitin-protein ligase BRE1A; Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). | 0.808 |
HIST1H2B5 | SETD2 | ENSGALP00000069619 | ENSGALP00000068801 | Histone H2B 5; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | SET domain containing 2, histone lysine methyltransferase. | 0.492 |
HIST1H2B5 | USP22 | ENSGALP00000069619 | ENSGALP00000056329 | Histone H2B 5; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Ubiquitin carboxyl-terminal hydrolase. | 0.478 |
HIST1H2B5L | H2BE1 | ENSGALP00000069556 | ENSGALP00000057898 | Histone H2B; Belongs to the histone H2B family. | Histone H2B; Belongs to the histone H2B family. | 0.409 |
HIST1H2B5L | HIST1H2B5 | ENSGALP00000069556 | ENSGALP00000069619 | Histone H2B; Belongs to the histone H2B family. | Histone H2B 5; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.405 |
HIST1H2B5L | HIST1H2B8 | ENSGALP00000069556 | ENSGALP00000056960 | Histone H2B; Belongs to the histone H2B family. | Histone H2B 8; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.405 |
HIST1H2B5L | HIST1H2BO | ENSGALP00000069556 | ENSGALP00000042437 | Histone H2B; Belongs to the histone H2B family. | Histone H2B 1/2/3/4/6; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.405 |