STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ETS2Protein C-ets-2; Probable transcription factor; Belongs to the ETS family. (479 aa)    
Predicted Functional Partners:
MAPK3
Mitogen-activated protein kinase.
   
 0.803
ETS1
Transforming protein p68/c-ets-1; Probable transcription factor.
     
0.764
RUNX1
Runt-related transcription factor.
   
 
 0.725
PAX5
Pax-5 protein.
   
 
 0.668
RUNX2
Runt-related transcription factor.
   
 
 0.638
PAX2
Paired-box containing protein Pax-2.
   
 
 0.617
TMEM121L
Uncharacterized protein.
      
 0.586
RUNX3
RUNX family transcription factor 3.
   
 
 0.582
JUN
Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. May be involved in activated KRAS-mediated transcriptional activation of USP28. May bind to the USP28 promoter; Belongs to the bZIP family. Jun subfamily.
   
 
 0.554
E4F1
E4F transcription factor 1.
   
 
 0.534
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.