node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ESRP1 | GRHL1 | ENSGALP00000048683 | ENSGALP00000045638 | Epithelial splicing regulatory protein 1. | TATA box-binding protein-associated factor RNA polymerase I subunit B. | 0.557 |
GLIS2 | GRHL1 | ENSGALP00000068250 | ENSGALP00000045638 | Uncharacterized protein. | TATA box-binding protein-associated factor RNA polymerase I subunit B. | 0.595 |
GRHL1 | ESRP1 | ENSGALP00000045638 | ENSGALP00000048683 | TATA box-binding protein-associated factor RNA polymerase I subunit B. | Epithelial splicing regulatory protein 1. | 0.557 |
GRHL1 | GLIS2 | ENSGALP00000045638 | ENSGALP00000068250 | TATA box-binding protein-associated factor RNA polymerase I subunit B. | Uncharacterized protein. | 0.595 |
GRHL1 | H3F3C | ENSGALP00000045638 | ENSGALP00000031320 | TATA box-binding protein-associated factor RNA polymerase I subunit B. | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] | 0.556 |
GRHL1 | HIST1H3H | ENSGALP00000045638 | ENSGALP00000042290 | TATA box-binding protein-associated factor RNA polymerase I subunit B. | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.556 |
GRHL1 | MAP7D1 | ENSGALP00000045638 | ENSGALP00000034427 | TATA box-binding protein-associated factor RNA polymerase I subunit B. | MAP7 domain containing 1. | 0.593 |
GRHL1 | SMARCA5 | ENSGALP00000045638 | ENSGALP00000037818 | TATA box-binding protein-associated factor RNA polymerase I subunit B. | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. | 0.589 |
GRHL1 | TAF1A | ENSGALP00000045638 | ENSGALP00000015355 | TATA box-binding protein-associated factor RNA polymerase I subunit B. | Uncharacterized protein. | 0.800 |
GRHL1 | TAF1C | ENSGALP00000045638 | ENSGALP00000042211 | TATA box-binding protein-associated factor RNA polymerase I subunit B. | TATA-box binding protein associated factor, RNA polymerase I subunit C. | 0.804 |
GRHL1 | TAF1D | ENSGALP00000045638 | ENSGALP00000066974 | TATA box-binding protein-associated factor RNA polymerase I subunit B. | Uncharacterized protein. | 0.800 |
GRHL1 | TBP | ENSGALP00000045638 | ENSGALP00000060826 | TATA box-binding protein-associated factor RNA polymerase I subunit B. | TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. | 0.802 |
H3F3C | GRHL1 | ENSGALP00000031320 | ENSGALP00000045638 | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] | TATA box-binding protein-associated factor RNA polymerase I subunit B. | 0.556 |
H3F3C | HIST1H3H | ENSGALP00000031320 | ENSGALP00000042290 | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.801 |
H3F3C | SMARCA5 | ENSGALP00000031320 | ENSGALP00000037818 | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. | 0.738 |
H3F3C | TAF1A | ENSGALP00000031320 | ENSGALP00000015355 | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] | Uncharacterized protein. | 0.499 |
H3F3C | TAF1C | ENSGALP00000031320 | ENSGALP00000042211 | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] | TATA-box binding protein associated factor, RNA polymerase I subunit C. | 0.499 |
H3F3C | TAF1D | ENSGALP00000031320 | ENSGALP00000066974 | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] | Uncharacterized protein. | 0.499 |
H3F3C | TBP | ENSGALP00000031320 | ENSGALP00000060826 | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] | TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. | 0.834 |
HIST1H3H | GRHL1 | ENSGALP00000042290 | ENSGALP00000045638 | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | TATA box-binding protein-associated factor RNA polymerase I subunit B. | 0.556 |