STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FARP1FERM, ARHGEF and pleckstrin domain-containing protein 1; Functions as guanine nucleotide exchange factor for RAC1 (By similarity). Plays a role in semaphorin signaling via its interaction with PLXNA4. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses. (1045 aa)    
Predicted Functional Partners:
ZFAND1
Zinc finger AN1-type containing 1.
      
 0.705
TMEM98
Transmembrane protein 98.
      
 0.587
XKRX
XK-related protein.
      
 0.533
KANSL3
KAT8 regulatory NSL complex subunit 3.
      
 0.533
CMSS1
Uncharacterized protein.
      
 0.533
SEMA6C
Semaphorin 6C; Belongs to the semaphorin family.
      
 0.516
YPEL5
Protein yippee-like; Belongs to the yippee family.
      
 0.510
PIP5K1C
PIPK domain-containing protein.
      
 0.503
BAIAP2L1
Uncharacterized protein.
     
 0.503
PLXNA4
Plexin A4.
      
 0.502
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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