STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITM2BIntegral membrane protein 2B; Plays a role in the induction of neurite outgrowth. Belongs to the ITM2 family. (262 aa)    
Predicted Functional Partners:
GRPEL2
GrpE like 2, mitochondrial.
   
  
 0.750
RCBTB2
RCC1 and BTB domain containing protein 2.
      
 0.711
PIANP
PILR alpha associated neural protein.
      
 0.703
AFAP1L1
Actin filament associated protein 1 like 1.
      
 0.702
TBC1D8B
TBC1 domain family member 8B.
      
 0.701
SPRYD7
SPRY domain-containing protein 7.
      
 0.700
JAGN1
Jagunal homolog 1.
      
 0.692
GNB1L
Uncharacterized protein.
   
  
 0.635
HS3ST4
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
  
 0.613
ESS2
Ess-2 splicing factor homolog.
      
 0.601
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.