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SPECC1L protein (Gallus gallus) - STRING interaction network
"SPECC1L" - Cytospin-A in Gallus gallus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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SPECC1LCytospin-A; Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration (By similarity) (1142 aa)    
Predicted Functional Partners:
ENSGALG00000025986
Uncharacterized protein (381 aa)
           
  0.819
ME1
Gallus gallus malic enzyme 1, NADP(+)-dependent, cytosolic (ME1), nuclear gene encoding mitochondrial protein, mRNA; Belongs to the malic enzymes family (650 aa)
       
 
  0.816
GOLGA5
Golgin A5 (735 aa)
           
  0.508
HOOK3
Hook microtubule-tethering protein 3 (722 aa)
           
  0.493
SOX6
Sox6 isoform 2; SRY (sex determining region Y)-box 6 (816 aa)
     
 
  0.486
PFDN4
Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (135 aa)
       
 
  0.479
DMD
Dystrophin; May play a role in anchoring the cytoskeleton to the plasma membrane (3085 aa)
           
  0.479
TXLNG
Taxilin gamma; Uncharacterized protein (486 aa)
           
  0.442
PRSS57
Protease, serine, 57; Belongs to the peptidase S1 family (300 aa)
           
  0.432
VIL1
Villin-1; Epithelial cell-specific Ca(2+)-regulated actin- modifying protein that modulates the reorganization of microvillar actin filaments. Plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing. Binds phosphatidylinositol 4,5-bisphosphate (PIP2) and lysophosphatidic acid (LPA); binds LPA with higher affinity than PIP2. Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities. Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity. Regulates the int [...] (805 aa)
     
 
  0.430
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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