STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXRA8Matrix remodeling-associated protein 8; Transmembrane protein which can modulate activity of various signaling pathways, probably via binding to integrin ITGAV:ITGB3. Mediates heterophilic cell-cell interactions in vitro. (467 aa)    
Predicted Functional Partners:
LDLRAD3
Low density lipoprotein receptor class A domain containing 3.
      
 0.837
B4GALT7
Beta1,4-galactosyltransferase 7.
      
 0.677
MED23
Mediator complex subunit 23.
      
 0.601
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase; Synthesis and degradation of fructose 2,6-bisphosphate; In the C-terminal section; belongs to the phosphoglycerate mutase family.
      
 0.558
MXRA7
Uncharacterized protein.
   
  
 0.525
FAM20C
FAM20C golgi associated secretory pathway kinase.
   
 
  0.505
TLDC1
MTOR-associated protein MEAK7; Activates an alternative mTOR signaling to regulate cell proliferation and migration.
   
  
 0.504
CAMK2B
Protein kinase domain-containing protein.
      
 0.489
CG-1B
Beta-galactoside-binding lectin; This protein binds beta-galactoside. May participate in host antiviral defense through specific interaction with glycans on the viral envelope glycoproteins.
   
 
  0.486
FAM20A
FAM20A golgi associated secretory pathway pseudokinase.
     
 0.475
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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