STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHACTR1Phosphatase and actin regulator 1; Binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers. (647 aa)    
Predicted Functional Partners:
KIAA1217
KIAA1217.
    
 
 0.715
ANO3
Anoctamin.
   
  
 0.714
TMEM178B
Uncharacterized protein.
      
 0.708
KCNG3
Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family.
      
 0.706
KCNT1
Potassium channel subfamily T member 1; Generates outwardly rectifying currents that are suppressed by elevation of intracellular calcium; Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa4.1/KCNT1 sub-subfamily.
      
 0.700
FBXO38
F-box protein 38.
      
 0.677
MEX3B
Mex-3 RNA binding family member B.
      
 0.601
IL12A
Interleukin-12 subunit alpha; Belongs to the IL-6 superfamily.
      
 0.600
PPP1R9A
Protein phosphatase 1 regulatory subunit 9A.
      
 0.600
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 
 0.594
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.