node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AP3S1 | RNF13 | ENSGALP00000003683 | ENSGALP00000038118 | Clat_adaptor_s domain-containing protein. | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | 0.788 |
AP3S1 | SNAPIN | ENSGALP00000003683 | ENSGALP00000041040 | Clat_adaptor_s domain-containing protein. | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] | 0.633 |
AP3S1 | UBE2E1 | ENSGALP00000003683 | ENSGALP00000018392 | Clat_adaptor_s domain-containing protein. | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. | 0.424 |
HSF2BP | RNF13 | ENSGALP00000026071 | ENSGALP00000038118 | Heat shock transcription factor 2 binding protein. | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | 0.794 |
HSF2BP | TMEM183A | ENSGALP00000026071 | ENSGALP00000054534 | Heat shock transcription factor 2 binding protein. | Uncharacterized protein. | 0.876 |
RNF128 | RNF13 | ENSGALP00000074288 | ENSGALP00000038118 | Ring finger protein 128. | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | 0.573 |
RNF13 | AP3S1 | ENSGALP00000038118 | ENSGALP00000003683 | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | Clat_adaptor_s domain-containing protein. | 0.788 |
RNF13 | HSF2BP | ENSGALP00000038118 | ENSGALP00000026071 | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | Heat shock transcription factor 2 binding protein. | 0.794 |
RNF13 | RNF128 | ENSGALP00000038118 | ENSGALP00000074288 | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | Ring finger protein 128. | 0.573 |
RNF13 | SDF2 | ENSGALP00000038118 | ENSGALP00000049430 | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | Stromal cell derived factor 2. | 0.599 |
RNF13 | SDF2L1 | ENSGALP00000038118 | ENSGALP00000062678 | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | Stromal cell derived factor 2 like 1. | 0.602 |
RNF13 | SNAPIN | ENSGALP00000038118 | ENSGALP00000041040 | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] | 0.791 |
RNF13 | TMEM183A | ENSGALP00000038118 | ENSGALP00000054534 | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | Uncharacterized protein. | 0.805 |
RNF13 | UBE2E1 | ENSGALP00000038118 | ENSGALP00000018392 | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. | 0.654 |
RNF13 | UBE2E3 | ENSGALP00000038118 | ENSGALP00000032683 | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.641 |
RNF13 | UBE2N | ENSGALP00000038118 | ENSGALP00000063826 | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.564 |
SDF2 | RNF13 | ENSGALP00000049430 | ENSGALP00000038118 | Stromal cell derived factor 2. | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | 0.599 |
SDF2L1 | RNF13 | ENSGALP00000062678 | ENSGALP00000038118 | Stromal cell derived factor 2 like 1. | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | 0.602 |
SNAPIN | AP3S1 | ENSGALP00000041040 | ENSGALP00000003683 | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] | Clat_adaptor_s domain-containing protein. | 0.633 |
SNAPIN | RNF13 | ENSGALP00000041040 | ENSGALP00000038118 | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase. May play a role in controlling cell proliferation, including that of muscle cells. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (By similarity). | 0.791 |