STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNT1Potassium channel subfamily T member 1; Generates outwardly rectifying currents that are suppressed by elevation of intracellular calcium; Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa4.1/KCNT1 sub-subfamily. (1343 aa)    
Predicted Functional Partners:
KCNMB4
Uncharacterized protein.
    
 
 0.845
C3orf67
Chromosome 3 open reading frame 67.
      
 0.845
HCN3
Cyclic nucleotide-binding domain-containing protein.
    
 
 0.724
PHACTR1
Phosphatase and actin regulator 1; Binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers.
      
 0.700
KCNN2
CaMBD domain-containing protein.
      
 0.667
KCNN1
Potassium calcium-activated channel subfamily N member 1.
      
 0.667
CDH22
Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins.
   
  
 0.639
PTPRN2
Protein tyrosine phosphatase receptor type N2.
      
 0.630
ZNF703
Zinc finger protein 703.
      
 0.630
KCNA4
Potassium channel Shaker cKv1.4; Belongs to the potassium channel family.
   
  
 0.616
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: high (84%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.