node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDC25A | CDC25B | ENSGALP00000057880 | ENSGALP00000068228 | Rhodanese domain-containing protein. | Cell division cycle 25B. | 0.909 |
CDC25A | PLK1 | ENSGALP00000057880 | ENSGALP00000009850 | Rhodanese domain-containing protein. | Serine/threonine-protein kinase PLK. | 0.975 |
CDC25A | YWHAB | ENSGALP00000057880 | ENSGALP00000043305 | Rhodanese domain-containing protein. | 14-3-3 protein beta/alpha; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity); Belongs to the 14-3-3 family. | 0.740 |
CDC25A | YWHAE | ENSGALP00000057880 | ENSGALP00000039133 | Rhodanese domain-containing protein. | 14-3-3 protein epsilon; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner; Belongs to the 14-3-3 family. | 0.803 |
CDC25A | YWHAG | ENSGALP00000057880 | ENSGALP00000027989 | Rhodanese domain-containing protein. | 14-3-3 protein gamma; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity); Belongs to the 14-3-3 family. | 0.715 |
CDC25A | YWHAZ | ENSGALP00000057880 | ENSGALP00000061765 | Rhodanese domain-containing protein. | 14-3-3 protein zeta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity). | 0.795 |
CDC25B | CDC25A | ENSGALP00000068228 | ENSGALP00000057880 | Cell division cycle 25B. | Rhodanese domain-containing protein. | 0.909 |
CDC25B | PLK1 | ENSGALP00000068228 | ENSGALP00000009850 | Cell division cycle 25B. | Serine/threonine-protein kinase PLK. | 0.978 |
CDC25B | YWHAB | ENSGALP00000068228 | ENSGALP00000043305 | Cell division cycle 25B. | 14-3-3 protein beta/alpha; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity); Belongs to the 14-3-3 family. | 0.948 |
CDC25B | YWHAE | ENSGALP00000068228 | ENSGALP00000039133 | Cell division cycle 25B. | 14-3-3 protein epsilon; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner; Belongs to the 14-3-3 family. | 0.960 |
CDC25B | YWHAG | ENSGALP00000068228 | ENSGALP00000027989 | Cell division cycle 25B. | 14-3-3 protein gamma; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity); Belongs to the 14-3-3 family. | 0.942 |
CDC25B | YWHAZ | ENSGALP00000068228 | ENSGALP00000061765 | Cell division cycle 25B. | 14-3-3 protein zeta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity). | 0.961 |
DENND1A | YWHAE | ENSGALP00000058471 | ENSGALP00000039133 | DENN domain containing 1A. | 14-3-3 protein epsilon; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner; Belongs to the 14-3-3 family. | 0.803 |
MLF1 | YWHAB | ENSGALP00000054567 | ENSGALP00000043305 | Uncharacterized protein. | 14-3-3 protein beta/alpha; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity); Belongs to the 14-3-3 family. | 0.406 |
MLF1 | YWHAE | ENSGALP00000054567 | ENSGALP00000039133 | Uncharacterized protein. | 14-3-3 protein epsilon; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner; Belongs to the 14-3-3 family. | 0.898 |
MLF1 | YWHAZ | ENSGALP00000054567 | ENSGALP00000061765 | Uncharacterized protein. | 14-3-3 protein zeta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity). | 0.438 |
PAFAH1B1 | PLK1 | ENSGALP00000009354 | ENSGALP00000009850 | Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration. | Serine/threonine-protein kinase PLK. | 0.804 |
PAFAH1B1 | YWHAE | ENSGALP00000009354 | ENSGALP00000039133 | Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration. | 14-3-3 protein epsilon; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner; Belongs to the 14-3-3 family. | 0.817 |
PLK1 | CDC25A | ENSGALP00000009850 | ENSGALP00000057880 | Serine/threonine-protein kinase PLK. | Rhodanese domain-containing protein. | 0.975 |
PLK1 | CDC25B | ENSGALP00000009850 | ENSGALP00000068228 | Serine/threonine-protein kinase PLK. | Cell division cycle 25B. | 0.978 |