node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTB | CALD1 | ENSGALP00000060844 | ENSGALP00000059428 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Caldesmon. | 0.994 |
ACTB | CALML3 | ENSGALP00000060844 | ENSGALP00000039444 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Calmodulin, striated muscle; Belongs to the calmodulin family. | 0.966 |
ACTB | CNN2 | ENSGALP00000060844 | ENSGALP00000053803 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. | 0.986 |
ACTB | CNN3 | ENSGALP00000060844 | ENSGALP00000063174 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. | 0.986 |
ACTB | MYLK | ENSGALP00000060844 | ENSGALP00000061379 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Myosin light chain kinase, smooth muscle, deglutamylated form; Phosphorylates a specific serine in the N-terminus of a myosin light chain, which leads to the formation of calmodulin/MLCK signal transduction complexes which allow selective transduction of calcium signals. | 0.522 |
CALD1 | ACTB | ENSGALP00000059428 | ENSGALP00000060844 | Caldesmon. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.994 |
CALD1 | CALML3 | ENSGALP00000059428 | ENSGALP00000039444 | Caldesmon. | Calmodulin, striated muscle; Belongs to the calmodulin family. | 0.994 |
CALD1 | CNN2 | ENSGALP00000059428 | ENSGALP00000053803 | Caldesmon. | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. | 0.861 |
CALD1 | CNN3 | ENSGALP00000059428 | ENSGALP00000063174 | Caldesmon. | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. | 0.870 |
CALD1 | MYLK | ENSGALP00000059428 | ENSGALP00000061379 | Caldesmon. | Myosin light chain kinase, smooth muscle, deglutamylated form; Phosphorylates a specific serine in the N-terminus of a myosin light chain, which leads to the formation of calmodulin/MLCK signal transduction complexes which allow selective transduction of calcium signals. | 0.449 |
CALML3 | ACTB | ENSGALP00000039444 | ENSGALP00000060844 | Calmodulin, striated muscle; Belongs to the calmodulin family. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.966 |
CALML3 | CALD1 | ENSGALP00000039444 | ENSGALP00000059428 | Calmodulin, striated muscle; Belongs to the calmodulin family. | Caldesmon. | 0.994 |
CALML3 | CAMK2A | ENSGALP00000039444 | ENSGALP00000009006 | Calmodulin, striated muscle; Belongs to the calmodulin family. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.974 |
CALML3 | CAMK2B | ENSGALP00000039444 | ENSGALP00000050970 | Calmodulin, striated muscle; Belongs to the calmodulin family. | Protein kinase domain-containing protein. | 0.972 |
CALML3 | CAMK4 | ENSGALP00000039444 | ENSGALP00000063204 | Calmodulin, striated muscle; Belongs to the calmodulin family. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.965 |
CALML3 | CNN2 | ENSGALP00000039444 | ENSGALP00000053803 | Calmodulin, striated muscle; Belongs to the calmodulin family. | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. | 0.963 |
CALML3 | CNN3 | ENSGALP00000039444 | ENSGALP00000063174 | Calmodulin, striated muscle; Belongs to the calmodulin family. | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. | 0.977 |
CALML3 | MYLK | ENSGALP00000039444 | ENSGALP00000061379 | Calmodulin, striated muscle; Belongs to the calmodulin family. | Myosin light chain kinase, smooth muscle, deglutamylated form; Phosphorylates a specific serine in the N-terminus of a myosin light chain, which leads to the formation of calmodulin/MLCK signal transduction complexes which allow selective transduction of calcium signals. | 0.975 |
CALML3 | PPP3CB | ENSGALP00000039444 | ENSGALP00000039533 | Calmodulin, striated muscle; Belongs to the calmodulin family. | Serine/threonine-protein phosphatase. | 0.967 |
CALML3 | PPP3CC | ENSGALP00000039444 | ENSGALP00000046851 | Calmodulin, striated muscle; Belongs to the calmodulin family. | Serine/threonine-protein phosphatase. | 0.966 |