node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC112531384 | PSMC1 | ENSGALP00000070326 | ENSGALP00000017347 | AAA_lid_3 domain-containing protein. | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | 0.999 |
LOC112531384 | PSMC2 | ENSGALP00000070326 | ENSGALP00000060323 | AAA_lid_3 domain-containing protein. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.999 |
LOC112531384 | PSMC5 | ENSGALP00000070326 | ENSGALP00000070654 | AAA_lid_3 domain-containing protein. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.999 |
LOC112531384 | PSMD11 | ENSGALP00000070326 | ENSGALP00000039931 | AAA_lid_3 domain-containing protein. | PCI domain-containing protein. | 0.998 |
LOC112531384 | PSMD12 | ENSGALP00000070326 | ENSGALP00000041149 | AAA_lid_3 domain-containing protein. | PCI domain-containing protein. | 0.999 |
LOC112531384 | PSMD13 | ENSGALP00000070326 | ENSGALP00000054631 | AAA_lid_3 domain-containing protein. | 26S proteasome non-ATPase regulatory subunit 13; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. | 0.998 |
LOC112531384 | PSMD2 | ENSGALP00000070326 | ENSGALP00000010153 | AAA_lid_3 domain-containing protein. | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.998 |
LOC112531384 | PSMD6 | ENSGALP00000070326 | ENSGALP00000067689 | AAA_lid_3 domain-containing protein. | Proteasome 26S subunit, non-ATPase 6. | 0.999 |
LOC112531384 | PSMD7 | ENSGALP00000070326 | ENSGALP00000000999 | AAA_lid_3 domain-containing protein. | Proteasome 26S subunit, non-ATPase 7. | 0.999 |
LOC112531384 | UBLCP1 | ENSGALP00000070326 | ENSGALP00000005808 | AAA_lid_3 domain-containing protein. | Ubiquitin-like domain-containing CTD phosphatase 1; Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome (By similarity). | 0.955 |
PSMC1 | LOC112531384 | ENSGALP00000017347 | ENSGALP00000070326 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | AAA_lid_3 domain-containing protein. | 0.999 |
PSMC1 | PSMC2 | ENSGALP00000017347 | ENSGALP00000060323 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.999 |
PSMC1 | PSMC5 | ENSGALP00000017347 | ENSGALP00000070654 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | AAA domain-containing protein; Belongs to the AAA ATPase family. | 0.999 |
PSMC1 | PSMD11 | ENSGALP00000017347 | ENSGALP00000039931 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | PCI domain-containing protein. | 0.999 |
PSMC1 | PSMD12 | ENSGALP00000017347 | ENSGALP00000041149 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | PCI domain-containing protein. | 0.999 |
PSMC1 | PSMD13 | ENSGALP00000017347 | ENSGALP00000054631 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | 26S proteasome non-ATPase regulatory subunit 13; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. | 0.999 |
PSMC1 | PSMD2 | ENSGALP00000017347 | ENSGALP00000010153 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. | 0.999 |
PSMC1 | PSMD6 | ENSGALP00000017347 | ENSGALP00000067689 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | Proteasome 26S subunit, non-ATPase 6. | 0.999 |
PSMC1 | PSMD7 | ENSGALP00000017347 | ENSGALP00000000999 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | Proteasome 26S subunit, non-ATPase 7. | 0.999 |
PSMC1 | UBLCP1 | ENSGALP00000017347 | ENSGALP00000005808 | 26S proteasome regulatory subunit 4; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | Ubiquitin-like domain-containing CTD phosphatase 1; Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome (By similarity). | 0.959 |