node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMH | CYP17A1 | ENSGALP00000051831 | ENSGALP00000032532 | TGF_BETA_2 domain-containing protein. | Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. | 0.874 |
AMH | CYP19A1 | ENSGALP00000051831 | ENSGALP00000066452 | TGF_BETA_2 domain-containing protein. | Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. | 0.883 |
AMH | FOXL2 | ENSGALP00000051831 | ENSGALP00000045929 | TGF_BETA_2 domain-containing protein. | Transcription factor FOXL2. | 0.957 |
AMH | NR0B1 | ENSGALP00000051831 | ENSGALP00000026210 | TGF_BETA_2 domain-containing protein. | NR LBD domain-containing protein. | 0.766 |
AMH | NR5A1 | ENSGALP00000051831 | ENSGALP00000001614 | TGF_BETA_2 domain-containing protein. | Uncharacterized protein. | 0.847 |
AMH | RSPO1 | ENSGALP00000051831 | ENSGALP00000003008 | TGF_BETA_2 domain-containing protein. | R-spondin 1. | 0.737 |
AMH | SOX9 | ENSGALP00000051831 | ENSGALP00000037718 | TGF_BETA_2 domain-containing protein. | Transcription factor SOX-9; Transcription factor that selectively activates enhancer through its interaction with a DNA-binding partner factor. Activates enhancer of COL2A1 through its binding with DNA sequence 5'-ATTCAT-3'. In response to bone morphogenetic protein stimulus, phosphorylation is induced and then sumoylation, allowing cooperation with SNAI2 to trigger neural crest delamination. Functions at the level of mesenchymal cell condensation by inducing cartilage development in limbs and by changing the aggregation properties of limb mesenchymal cells. Regulates the cell fate dec [...] | 0.855 |
AMH | WT1 | ENSGALP00000051831 | ENSGALP00000019761 | TGF_BETA_2 domain-containing protein. | Uncharacterized protein. | 0.772 |
CYP17A1 | AMH | ENSGALP00000032532 | ENSGALP00000051831 | Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. | TGF_BETA_2 domain-containing protein. | 0.874 |
CYP17A1 | CYP19A1 | ENSGALP00000032532 | ENSGALP00000066452 | Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. | Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. | 0.959 |
CYP17A1 | FOXL2 | ENSGALP00000032532 | ENSGALP00000045929 | Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. | Transcription factor FOXL2. | 0.706 |
CYP17A1 | NR0B1 | ENSGALP00000032532 | ENSGALP00000026210 | Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. | NR LBD domain-containing protein. | 0.732 |
CYP17A1 | NR5A1 | ENSGALP00000032532 | ENSGALP00000001614 | Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. | Uncharacterized protein. | 0.870 |
CYP17A1 | SOX9 | ENSGALP00000032532 | ENSGALP00000037718 | Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. | Transcription factor SOX-9; Transcription factor that selectively activates enhancer through its interaction with a DNA-binding partner factor. Activates enhancer of COL2A1 through its binding with DNA sequence 5'-ATTCAT-3'. In response to bone morphogenetic protein stimulus, phosphorylation is induced and then sumoylation, allowing cooperation with SNAI2 to trigger neural crest delamination. Functions at the level of mesenchymal cell condensation by inducing cartilage development in limbs and by changing the aggregation properties of limb mesenchymal cells. Regulates the cell fate dec [...] | 0.513 |
CYP17A1 | WT1 | ENSGALP00000032532 | ENSGALP00000019761 | Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. | Uncharacterized protein. | 0.454 |
CYP19A1 | AMH | ENSGALP00000066452 | ENSGALP00000051831 | Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. | TGF_BETA_2 domain-containing protein. | 0.883 |
CYP19A1 | CYP17A1 | ENSGALP00000066452 | ENSGALP00000032532 | Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. | Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. | 0.959 |
CYP19A1 | FOXL2 | ENSGALP00000066452 | ENSGALP00000045929 | Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. | Transcription factor FOXL2. | 0.959 |
CYP19A1 | NR0B1 | ENSGALP00000066452 | ENSGALP00000026210 | Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. | NR LBD domain-containing protein. | 0.728 |
CYP19A1 | NR5A1 | ENSGALP00000066452 | ENSGALP00000001614 | Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. | Uncharacterized protein. | 0.854 |