STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F10Activated factor Xa heavy chain; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. VAP cleaves the fusion proteins of Sendai virus, NDV, and influenza virus a at a specific single arginine- containing site, and plays a key role in the viral spreading in the allantoic sac; Belongs to the peptidase S1 family. (475 aa)    
Predicted Functional Partners:
F2
Uncharacterized protein; Belongs to the peptidase S1 family.
  
0.885
F5
Coagulation factor V; Belongs to the multicopper oxidase family.
   
 0.850
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
   
 0.834
SERPINC1
Antithrombin-III; Belongs to the serpin family.
   
 0.801
F3
Coagulation factor III, tissue factor.
    
 0.796
FURIN
Trans Golgi network protease furin; Belongs to the peptidase S8 family.
  
 
 0.782
F7
Uncharacterized protein.
  
 
0.782
F9
Coagulation factor IXa heavy chain; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
  
 
 
0.773
TFPI
Tissue factor pathway inhibitor.
   
 0.725
VAPA
MSP domain-containing protein.
    
 
 0.716
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.