node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CST3 | CSTB | ENSGALP00000043172 | ENSGALP00000023239 | Cystatin; This protein binds tightly to and inhibits a variety of thiol proteases including ficin, papain, and cathepsins B, C, H, and L. Although isolated from egg white, it is also present in serum. | Cystatin domain-containing protein; Belongs to the cystatin family. | 0.856 |
CST3 | CTSB | ENSGALP00000043172 | ENSGALP00000061589 | Cystatin; This protein binds tightly to and inhibits a variety of thiol proteases including ficin, papain, and cathepsins B, C, H, and L. Although isolated from egg white, it is also present in serum. | Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis; Belongs to the peptidase C1 family. | 0.893 |
CST3 | CTSH | ENSGALP00000043172 | ENSGALP00000051767 | Cystatin; This protein binds tightly to and inhibits a variety of thiol proteases including ficin, papain, and cathepsins B, C, H, and L. Although isolated from egg white, it is also present in serum. | Uncharacterized protein; Belongs to the peptidase C1 family. | 0.830 |
CST3 | CTSS | ENSGALP00000043172 | ENSGALP00000065590 | Cystatin; This protein binds tightly to and inhibits a variety of thiol proteases including ficin, papain, and cathepsins B, C, H, and L. Although isolated from egg white, it is also present in serum. | Uncharacterized protein; Belongs to the peptidase C1 family. | 0.888 |
CST3 | CTSV | ENSGALP00000043172 | ENSGALP00000020559 | Cystatin; This protein binds tightly to and inhibits a variety of thiol proteases including ficin, papain, and cathepsins B, C, H, and L. Although isolated from egg white, it is also present in serum. | Cathepsin L1 heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family. | 0.891 |
CST3 | LGMN | ENSGALP00000043172 | ENSGALP00000017556 | Cystatin; This protein binds tightly to and inhibits a variety of thiol proteases including ficin, papain, and cathepsins B, C, H, and L. Although isolated from egg white, it is also present in serum. | Legumain. | 0.890 |
CST3 | LOC101749502 | ENSGALP00000043172 | ENSGALP00000064757 | Cystatin; This protein binds tightly to and inhibits a variety of thiol proteases including ficin, papain, and cathepsins B, C, H, and L. Although isolated from egg white, it is also present in serum. | Uncharacterized protein. | 0.844 |
CST3 | LOC420160 | ENSGALP00000043172 | ENSGALP00000006754 | Cystatin; This protein binds tightly to and inhibits a variety of thiol proteases including ficin, papain, and cathepsins B, C, H, and L. Although isolated from egg white, it is also present in serum. | Uncharacterized protein; Belongs to the peptidase C1 family. | 0.893 |
CST3 | OVST | ENSGALP00000043172 | ENSGALP00000047323 | Cystatin; This protein binds tightly to and inhibits a variety of thiol proteases including ficin, papain, and cathepsins B, C, H, and L. Although isolated from egg white, it is also present in serum. | Ovostatin; Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). | 0.786 |
CST3 | OVSTL | ENSGALP00000043172 | ENSGALP00000051424 | Cystatin; This protein binds tightly to and inhibits a variety of thiol proteases including ficin, papain, and cathepsins B, C, H, and L. Although isolated from egg white, it is also present in serum. | Uncharacterized protein. | 0.805 |
CSTB | CST3 | ENSGALP00000023239 | ENSGALP00000043172 | Cystatin domain-containing protein; Belongs to the cystatin family. | Cystatin; This protein binds tightly to and inhibits a variety of thiol proteases including ficin, papain, and cathepsins B, C, H, and L. Although isolated from egg white, it is also present in serum. | 0.856 |
CSTB | CTSB | ENSGALP00000023239 | ENSGALP00000061589 | Cystatin domain-containing protein; Belongs to the cystatin family. | Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis; Belongs to the peptidase C1 family. | 0.820 |
CSTB | CTSS | ENSGALP00000023239 | ENSGALP00000065590 | Cystatin domain-containing protein; Belongs to the cystatin family. | Uncharacterized protein; Belongs to the peptidase C1 family. | 0.698 |
CSTB | CTSV | ENSGALP00000023239 | ENSGALP00000020559 | Cystatin domain-containing protein; Belongs to the cystatin family. | Cathepsin L1 heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family. | 0.644 |
CSTB | LOC420160 | ENSGALP00000023239 | ENSGALP00000006754 | Cystatin domain-containing protein; Belongs to the cystatin family. | Uncharacterized protein; Belongs to the peptidase C1 family. | 0.599 |
CTSB | CST3 | ENSGALP00000061589 | ENSGALP00000043172 | Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis; Belongs to the peptidase C1 family. | Cystatin; This protein binds tightly to and inhibits a variety of thiol proteases including ficin, papain, and cathepsins B, C, H, and L. Although isolated from egg white, it is also present in serum. | 0.893 |
CTSB | CSTB | ENSGALP00000061589 | ENSGALP00000023239 | Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis; Belongs to the peptidase C1 family. | Cystatin domain-containing protein; Belongs to the cystatin family. | 0.820 |
CTSB | CTSH | ENSGALP00000061589 | ENSGALP00000051767 | Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis; Belongs to the peptidase C1 family. | Uncharacterized protein; Belongs to the peptidase C1 family. | 0.586 |
CTSB | CTSS | ENSGALP00000061589 | ENSGALP00000065590 | Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis; Belongs to the peptidase C1 family. | Uncharacterized protein; Belongs to the peptidase C1 family. | 0.609 |
CTSB | CTSV | ENSGALP00000061589 | ENSGALP00000020559 | Cathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis; Belongs to the peptidase C1 family. | Cathepsin L1 heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family. | 0.633 |