STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HES6Hes family bHLH transcription factor 6. (242 aa)    
Predicted Functional Partners:
EBF4
EBF family member 4.
      
 0.702
DLL1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 
 0.682
ASCL1
BHLH domain-containing protein.
    
 
 0.652
BTG2
BTG anti-proliferation factor 2.
      
 0.616
NEUROD1
Neurogenic differentiation factor 1; Acts as a transcriptional activator. Mediates transcriptional activation by binding to E box-containing promoter. Acts as a differentiation factor during neurogenesis. Induces photoreceptor cell overproduction in vivo and de novo generation in vitro. May play a role in photoreceptor cell production. Binds DNA on E-box consensus sequence 5'-CANNTG-3'.
    
 
 0.550
NHLH1
BHLH domain-containing protein.
    
 
 0.511
BARHL1
BarH like homeobox 1.
    
 
 0.502
GSX2
GS homeobox 2.
    
 
 0.495
MSC
Musculin.
    
 
 0.487
JAG1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 
 0.486
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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