STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADT88793.1NAD-dependent aldehyde dehydrogenase; COG1012; Belongs to the aldehyde dehydrogenase family. (506 aa)    
Predicted Functional Partners:
acsA
acetyl-CoA synthase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.936
ADT87835.1
Zn-dependent alcohol dehydrogenase, class III; COG1062; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.920
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.916
ackA-2
Acetate/propionate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.916
ADT86479.1
Alcohol dehydrogenase/acetaldehyde dehydrogenase; COG1012; COG1979; COG1454; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.915
ADT89594.1
Alcohol dehydrogenase, class IV; COG1979; COG1454.
 
 0.915
ADT88507.1
D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG1064.
  
 
 0.912
ADT87128.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
    
 0.908
ADT87168.1
Acylphosphatase; COG1254.
    
 0.905
ADT89613.1
acetyl-coA:acetoacetyl-coA transferase alpha subunit; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.
     
 0.901
Your Current Organism:
Vibrio furnissii
NCBI taxonomy Id: 903510
Other names: V. furnissii NCTC 11218, Vibrio furnissii NCTC 11218, Vibrio furnissii str. NCTC 11218, Vibrio furnissii strain NCTC 11218
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